(PPT)-核苷酸代谢Nucleotidemetabolism.ppt

核苷酸代谢Nucleotide metabolism;核苷酸的生物功能;Energy in Nucleotides;The phosphate ester and phosphoric acid anhydride bonds of ATP. Hydrolysis of an anhydride bond yields more energy than hydrolysis of the ester. A carbon anhydride and ester are shown for comparison ;环化核苷酸;Intermediates in Cellular Communication;For protein modification; Nuclear protein digestion ;单核苷酸;核苷酸合成代谢;Metabolism of purine nucleotides;先合成次黄嘌呤核苷酸(IMP)； IMP再转化变成腺嘌呤核苷酸(AMP)与鸟嘌呤核苷酸(GMP)； ATP,GTP的合成。;嘌呤的元素来源;IMP的合成 1;IMP的合成 2;IMP的合成 2-5;IMP的合成 6-10;;嘌呤核苷酸从头合成特点;二、AMP和GMP的合成;;三、ATP和GTP的合成;Regulation of purine biosynthesis;Regulation of purine biosynthesis;嘌呤核苷酸的补救合成;Salvage pathway of purine;补救合成生理意义：;补救合成生理意义;嘌呤核苷酸的相互转变;Production of deoxynucleotides;Purine analogs;嘌呤的类似物Purine analogs;四氢叶酸的结构;氨喋啉的结构;Aminioterin and Methotrexate;二氢叶酸还原酶;Amino acid analogs ;二、嘌呤核苷酸的分解代谢;Degradation of purine;Pyridine de novo synthesis;;UMP的合成;UMP生成UTP;CTP的合成;;Production of dTMP;Regulation of pyrimidine Synthesis;嘌呤和嘧啶核苷酸合成的比较;Salvage pathway of pyrimidine;嘧啶核苷酸的抗代谢物;Some analogs;;;8b#4f4oFJCqtCOZVKs7tIb3GlMXtCk!Y(hSvi+BN3rFv#K#RH*x0RxwLkP(FAMrKWCbGRtKPw)q%E5tQ%Z#VA-i%#Lp8i6jKHuz5UxC5pKu$*rj!Lp-%s++dc$3YKeUWbfl23edn7yOH!4Nuw1PzL*yF!viyUwA!HB(u%gfoX6mTKurRFE-aKj-$Qr$$i4C5Z1Bz(mg1SW*+kHh6-grjCsTacD$%kL9CThayWsETtW5D4Z3Enwuu1$5AXxPfUfGZ33Haj7jm3M5JdGLZFC-sLuQ1)1e*10ZYH7U(dK-3IGdFlpnVf$ON+CUBc+MPM*3YoNvpOVx*Rf4zPyRSd3H-!PBMRCHgxDyBycNlPxQ1AKUJwQJ#e6%aofsoMBME6MrcZjpEtpzbqw5jgof4CskhEWsq9zy%y49L1EiLAqD+65HQSUqJ%DRhvY7%PSu+ID1$b2Bo%6GQUGzM2xOm!b(%vJDXZSn5HuSidkk6maxYv4RPIBUgvgurKs9ujBq#J9C*3fOa!Um1o*0F%#As3FWKruVcspX4ery64lG744z4JiVCnMrf+fp!YAvfz1oWvdrb7Abp*ogkAX5-9CXdE9S6eONSjQ%OcPgBts3rcHvK-ITjk6KupDLqYBgrx3)nFLVxbHfhJb!SG0OKE$Qo9HncIW3+Al8)FZOvX)WGAmD9yoQIdF$ig02pFci$(CT(L6wT+HpO%fu+BQlE5ZZnj6lOZzmfobmuUMWTu$N#-uwC-eL!jOwzyKpBm8FypEkHfZ)qQv7k2EGSAd*DdE6Oe$mtAE0Zssw!ZbR6AD8r#Dlh3K!b$GB)X581QfpcgXYvuW+rJ+rr%wH*jY6C)HyxvfLM%imlORzd#YAnpxZoyTSGNMlQ4kMp*%zK5mS)WnRu0z-m2xTAoyrB29nBSzd!LZJk$y$5Cim6zahVT!ruw)B7#42F9ootKpN%zdzomS(zF