Abstract - International Conferences on Improving Use of …提高使用抽象的国际会议….ppt

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2018-06-24 发布于上海
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Abstract - International Conferences on Improving Use of …提高使用抽象的国际会议….ppt

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Abstract - International Conferences on Improving Use of …提高使用抽象的国际会议…

Baseline Data and Predictors of Adherence in Patients on Antiretroviral Therapy in Maun General Hospital [MGH], Maun, BotswanaNwokike J.I. [B.Pharm, MSc. Pharmacology]Maun General HospitalMaun. Rep. Of Botswana. ABSTRACT Background: In Botswana, there is a lack of baseline data to determine the level of adherence to Antiretroviral (ARV) drugs. Objective: This study is an institution-based, quantitative and retrospective study designed to determine baseline adherence values and identify predictors of adherence amongst treatment -experienced patients. Poplation and Setting: The study involved 176 experienced (three months of treatment) patients on Antiretroviral drugs at MGH, one of the project sites of the Botswana National Antiretroviral Program. Eligible patients were all the 176 ambulatory patients treated for at least 3 months. Their files were analyzed for adherence reports. Method: The adherence measurement instruments used were the 7 days recall self completed questionnaire and pill counts. Pills Identification tests, structured interviews and Monthly Pill Calendar counterbalanced the vulnerability of these methods to fabrications. The study had a zero tolerance to nonadherence. In the follow-up study, 182 three- months experienced patients were administered self-complete questionnaires. Results: From the 176 patient records reviewed, there was a determined average adherence per month value of 24.948days [83.16%]. Most patients [54.39%] were on a Combivir/Efavirenz combination. This patient group had 24.99adherent days/month [upper 95% confidence interval of 25.72]. Adherence to a Combivir/Nevirapine combination was 29.82 adherent days/month [95% confidence interval of 26.37, P value for the two groups =0.10] Adherence promoters were found to be Adherence Partners (51 patients out of 182 [28.02%]), Pharmacy counseling (48 or 26.37%) and Pill count at 32 [17.58%]. Nonadherence predictors include Forgot (49 patients [26.92%]), Access (37 [20.33%]) and L