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Original papers Med Ultrason 2015, Vol. 17, no. 4, 444-450
DOI: 10.11152/mu.2013.2066.174.csu
Contrast enhanced ultrasound for the diagnosis of liver hemangiomas
– results of a Romanian multicentre study.
1 1 2 1 1
Roxana Şirli , Ioan Sporea , Daniela Larisa Săndulescu , Alina Popescu , Mirela Dănilă ,
2 3 3
Adrian Săftoiu , Zeno Spârchez , Radu Badea
1Department of Gastroenterology and Hepatology, “Victor Babeş” University of Medicine and Pharmacy Timişoara,
2 3
Centre for Research in Gastroenterology and Hepatology, University of Medicine and Pharmacy Craiova, Regional
Institute of Gastroenterology and Hepatology “Prof. Dr. Octavian Fodor”, ”Iuliu Hațieganu” University of Medicine
and Pharmacy Cluj Napoca, Romania
Abstract
Background and aim: Contrast enhanced ultrasound (CEUS) has been proven to be a reliable method for the charac-
terization of focal liver lesions (FLL). The aim of this paper was to evaluate the performance of CEUS for the diagnosis of
liver hemangiomas in a large cohort of patients. Material and method: We performed a multicentre prospective study which
included successive CEUS examinations from fourteen centers from Romania. CEUS examinations were performed in de
novo FLL, using low mechanical index ultrasound, following an intravenous bolus of 2.4 ml SonoVue. CEUS was considered
conclusive for hemangioma if a typical pattern was present following contrast (centripetal fill in dur
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