大剂量阿托伐他汀对糖尿病急性前壁心肌梗死溶栓效果影响.docVIP

大剂量阿托伐他汀对糖尿病急性前壁心肌梗死溶栓效果影响 　　[摘要] 目的 探究大剂量阿托伐他汀对糖尿病急性前壁心肌梗死溶栓效果的影响。方法 选取该院2012年3月―2015年3月收治的糖尿病急性前壁心肌梗死患者100例作为该次的观察对象，按照随机数字法分为两组，分别为研究组和对照组。对照组患者50例，采用常规治疗方案；研究组患者50例，在溶栓治疗前给予80 mg阿托伐他汀口服，比较两组患者溶栓前后的血浆高敏C反应蛋白水平与超声心动图检查情况。结果 经过临床治疗后，研究组患者的再通率为74.0%，对照组为46.0%，比较两组患者的再通率差异有统计学意义（P0.05）；研究组患者的高敏C反应蛋白的改善情况明显优于对照组（P0.05）；两组患者治疗后的舒张末期（收缩末期）容积指数与左心室射血分数明显改善（P0.05），且研究组患者的改善程度明显优于对照组（P0.05）。结论 对糖尿病急性前壁心肌梗死患者给予阿托伐他汀治疗的临床效果显著，可使得溶栓再通率明显增加，改善患者临床症状，值得推广并应用。 　　[关键词] 糖尿病；前壁心肌梗死；溶栓；阿托伐他汀 　　[中图分类号] R587.2 [文献标识码] A [文章编号] 1672-4062（2016）04（a）-0024-03 　　[Abstract] Objective To explore the high-dose atorvastatin laval dean of diabetes with acute anterior wall myocardial infarction thrombolysis effect. Methods Select our hospital in March 2012 - March 2015 diabetic patients with acute anterior wall myocardial infarction treated 100 cases as the observation object， is divided into two groups according to random number method， research group and the control group respectively. The control group， 50 cases of patients with the conventional treatment； 50 patients with team， before thrombolysis treatment given 80 mg of atorvastatin oral， compared two groups of patients before and after thrombolysis plasma high-sensitivity c-reactive protein levels and echocardiographic examination. Results of After clinical treatment group at the rate of the patients was 74.0%， control group was 46.0%， the comparison of two groups of patients with significant difference（P0.05）； the rate of The team to improve the situation of high-sensitivity c-reactive protein in patients with significantly better than that of control group（P0.05）； Two groups of patients after treatment of end-diastolic volume index （end systolic） and left ventricular ejection fraction obviously improved（P0.05）， and improved group patients was significantly better than the control group（P0.05）. Conclusion In diabetic patients with acute anterior wall myocardial infarction given atorvastatin therapy clinical effect is remarkable， thr