孟鲁司特钠在儿科哮喘治疗中临床应用效果分析.docVIP

孟鲁司特钠在儿科哮喘治疗中临床应用效果分析 　　[摘要]目的 研究孟鲁司特钠在儿科哮喘治疗中的临床应用价值与治疗效果。方法 整群选取该院在2013年10月―2014年10月间收治的76例哮喘患儿的临床资料，根据数字随机分组法原则，将患儿分为两组，每组38例。对照组采用布地奈德吸入治疗，观察组除采用布地奈德吸入治疗外，还给予孟鲁司特纳进行治疗，比较两组患儿的治疗效果与肺功能指标变化情况。结果 ①观察组治疗总有效率为97.37%，对照组治疗总有效率为81.58%，与对照组相比，观察组治疗有效率更好，对比差异有统计学意义（P0.05）。②治疗后，观察组肺功能指标改善效果优于对照组，差异有统计学意义（P0.05）。 结论 孟鲁司特钠的使用可以改善患儿肺功能指标，同时可提升治疗有效率，减轻患儿痛苦，尽早缓解其疾病症状，值得临床推广应用。 　　[关键词] 孟鲁司特钠；哮喘；临床疗效 　　[中图分类号] R725.6 [文献标识码] A [文章编号] 1674-0742（2015）06（c）-0132-02 　　[Abstract] Objective To study the therapeutic effect of montelukast in the treatment of pediatric asthma. Methods The clinical data of a total of 76 patients with pediatric asthma admitted to our hospital between October 2013 and October 2014 were selected and randomly divided into two groups， 38 patients in each group. Patients in the control group were treated with the inhalation of budesonide， while those in the treatment group were given montelukast based on inhalation of budesonide. Curative effect and changes of lung function index of the two groups were compared. Results ①The total effective rate of treatment group， 97.37%， was higher than that of the control group ，81.58%， and the difference was statistically significant （P0.05）. ②After treatment， the effect of the improvement of lung function of the observation was better than that of the control group， and the difference was statistically significant （P0.05）. Conclusion Montelukast can not only improve lung function of the children and treatment efficiency， but also relieve pain and alleviate symptoms of the disease as soon as possible， so it is worthy of clinical popularization and application. 　　[Key words] Montelukast； Asthma； Clinical curative effect 　　小儿哮喘属于慢性呼吸道疾病，患儿最主要的临床表现为气道高反应，导致患儿发生胸闷、喘息、气促等症状，若治疗不及时，便会损害肺部功能，出现疾病久治不愈的情况，严重情况下，会对患儿生命构成威胁[1]。近几年，孟鲁斯特纳的应用使小儿哮喘疾病的临床疗效有了很大提升，该研究主要分析孟鲁司特钠在儿科哮喘治疗中的临床应用价值与治疗效果，整群选取该院收治的76例病例进行研究，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　该院在2013年10月―2014年10月间收治的76例哮喘患儿为研究对象，根据数字随机分组法原则，将患儿分为两组，每组各38例病例。对照组采用布地奈德吸入治疗，男患儿20例，女