雾化吸入布地奈德与异丙托溴胺治疗老年性慢性阻塞性肺病效果分析.docVIP

雾化吸入布地奈德与异丙托溴胺治疗老年性慢性阻塞性肺病效果分析 　　[摘要]目的 探究雾化吸入布地奈德与异丙托溴胺治疗老年性慢性阻塞性肺病（COPD）的临床效果。方法 选取2015年1月～2016年6月我院收治的拟行腹腔镜手术且经确诊为中重度COPD患者60例为研究对象，采用随机数字表法分为研究组和对照组，每组各30例。研究组给予雾化吸入布地奈德与异丙托溴胺治疗，对照组给予生理盐水进行雾化治疗。观察和比较两组患者治疗前5 min和雾化治疗后10 min的气道压峰值，麻醉前不吸氧状态下和麻醉苏醒后不吸氧自主呼吸10 min后的SpO2、动脉血气的pH值、氧分压（PaO2）、二氧化碳分压（PaCO2），比较术后两组患者的拔管情况。结果 治疗前5 min两组患者术中气道峰压指标差异无?y计学意义（P0.05），治疗后10 min研究组患者的术中气道峰压显著低于对照组。不同时点研究组患者的SpO2、PaO2显著高于对照组，PaCO2显著低于对照组；研究组患者的术后1 h内拔管成功率为90.00%，显著高于对照组的56.67%；差异均有统计学意义（P0.05）。结论 雾化吸入布地奈德与异丙托溴胺治疗老年性COPD的临床效果显著，是临床治疗的理想选择。 　　[关键词]雾化吸入；布地奈德；异丙托溴胺；慢性阻塞性肺病 　　[中图分类号] R563.9 [文献标识码] A [文章编号] 1674-4721（2017）10（b）-0018-03 　　[Abstract]Objective To explore the clinical therapeutic effect of aerosol inhalation of Budesonide and Ipratropium bromide in the treatment of senile chronic obstructive pulmonary disease.Methods From January 2015 to June 2016，60 patients with moderate to severe chronic obstructive pulmonary disease were selected as research object.They were randomly divided into study group and control group by random number table，30 cases in each group.The study group were given inhaled Budesonide and Ipratropium bromide treatment，the control group were given inhaled with stioke physiscogical saline solation.Peak airway pressure of 10 min before and after treatment with 5 min，SpO2，arterial blood gas pH value，partial pressure of oxygen，partial pressure of carbon dioxide of before anesthesia without oxygen state and after anesthesia recovery without oxygen inhalation after 10 min were observed and compared between the two groups.Results Before the treatment of 5 min two groups of patients with peak pressure，the difference had no statistical significance （P0.05），after the treatment of airway 10 min study group of patients with peak pressure was significantly lower than the control group.The SpO2，PaO2 of the study group of patients were significantly higher than the control group，the partial pressure of carbon dioxide was significantly lower than the control group；the