IU患者凝血功能变化及其与血钙水平的相关性分析.doc

ICU患者凝血功能变化及其与血钙水平的相关性分析 古声燕 成都医学院第一附属医院四川成都610000 】目的：分析ICU患者凝血功能变化及其与血钙水平的相关性。方 法：以我院ICU收治的78例患者为研究对象，分别检测患者的凝血功能指标， 括血小板计数(PLT)、血小板压积(PCT)、凝血酶原时间(PT)、凝血酶原活 动度(P)、凝血酶原时间比值(PTR)、国际标准化比值(INR)及血清总钙(TCa)。 并根据检测结果对比分析不同病情程度下患者的凝血功能指标水平和TCa指标 水平，对比分析正常血钙组患者与低钙血症组患者的凝血功能指标水平。结果: 在凝血指标PLTT、PCT、卩及1^3指标值上，较度组〉中度组〉重度组(P0.05); 在PT、PTR、INR指标值上，轻度组中度组重度组(P0.05)o正常血钙组 患者的TCa、PLTT、PCT指标值均高于低钙血症组(P0.05), PTR、INR指标值 均低于低钙血症组(P0.05)。患者凝血功能指标PLTT与TCa呈正相关(「=0.212， P=0.028)，PCT 与 TCa 呈正相关(r=0.205, P=0.031), PTR 与 TCa 呈负相关(「=-0.451， P=0.035), INR与TCa呈负相关(r=-0.577, P=0.032)。结论:凝血功能指标及TCa 水平均与ICU患者的病情密切相关，1.相关凝血功能指标与TCa具有一定的相关 性，通过二者的监测对疾病的治疗具有指导意义。 关键词】ICU;凝血功能；血钓；相关性 1R446.5 】B 】1674-8999( 2015 ) 8-0286-02 Abstract】 objective: Analyze of the changes of coagulation function of patients with ICU and its correlation with serum calcium level. Methods: 78 patients of our hospital ICU were as the research object, the patients of coagulant function index were tested, including platelet count (PLT), platelet deposited (PCT), prothrombin time (PT) and prothrombin activity (P), prothrombin time ratio (PTR), international standardization ratio (INR) and total serum calcium (TCa). According to the test results, comparative analysis under different degree of disease in patients with blood coagulation function index level and TCa index level, compared to normal blood calcium group of patients with hypocalcemia group of patients with blood coagulation function index level. Results: the coagulation indexes PLTT, PCT, P and TCa parameter values, the mild group gt; moderate gt; severe group (P lt; 0.05); On PT, PTR, INR indexes, mild lt; moderate group lt; severe group (P lt; 0.05). Normal blood calcium group of patients with TCa, PLTT, PCT indexes were higher than in hypocalcemia group (P lt; 0.05), PTR, INR indexes were lower than that of hypocalcemia group (P lt; 0.05). Blood coagulation function in patients with index PLTT was positively related with TCa (r = 0.212, P = 0.212), PCT and TCa