丹葛止痛汤对实验性亚急性心肌缺血大鼠心肌血管形态的影响中西医结合;临床专业论文.docx

日后,取心肌作病理切片,厚60μm, 脱水透明,中性树脂胶封片,光镜观 察分析。用统计软件SPASS3.1软件包对数据进行统计学处理。 实验结果：正常对照组、丹葛止痛汤小剂量组与模型组比较，大鼠心肌 显影血管数目及显影血管面积总和均高于模型组，差异有统计学意义 （p0.05）；丹葛止痛汤小剂量组、丹葛止痛汤高剂量组及消心痛组与 模型组比较，大鼠心肌显影血管数目及显影血管面积总和均高于模型组， 差异有统计学意义（p0.01）；丹葛止痛汤小剂量组、丹葛止痛汤高剂 量组与消心痛组比较，大鼠心肌显影血管数目及显影血管面积总和小于 消心痛组，差异有统计学意义（p0.05）。 结论：中药方剂丹葛止痛方能明显提高大鼠缺血心肌显影血管数目及显 影血管面积总和，其疗效低于消心痛。提示丹葛止痛汤对心肌缺血有一 定的保护作用，是一种防治心肌缺血的有效药物，值得进一步深入地系 统研究。 关键词：丹葛止痛汤；心肌缺血大鼠；血管形态 5 The study of effects of traditional Chinese medicine- Dangezhitongtang on Vascular morphology in Rats with Sub -acute Myocardial ischemia Acute Myocardial Ischemia ABSTRACT Objective: This study was designed to observe the effects of prescri- ption animal Dange analgesic decoction on rat myocardial ischemia model of subacute myocardial vascular morphology is proposed from a morphological perspective Dange microvascular analgesic decoction on myocardial ischemia in the mechanism for clinical medicine to provide theoretical and experimental basis. Methods: Take SD rats, male and female, 80 only 200 - weight evenly 300g, 80 rats, first cardiogram to st-segment, abnormal change and ShiChangZhe rhythm. Only by 75 in rats were randomly divided into 5 groups, the method of each group, i.e. 15 only normal control group (group), model group (group B), XiaoXinTong group (C) (2.7 mg/kg), Dan Gregory analgesic soup high-dosage groups (D) (out 28g/kg), low doses of painkillers soup Dan ge (E) (equivalent 7g out/kg). To medicine, once-daily dosage, respectively, pushing object surface conversion. TCM Dan Gregory analgesic soup group from the first day, TCM Dan Gregory analgesic soup by high-dose (out 28g/kg), Dan ge by small doses of painkillers soup out (7g/kg) in the way of rats fed medicine, 1 times per day, 30 days, Group C from the first day, giving XiaoXinTong slice salt dissolving) temperature (2.7 mg/kg, to medicine, 1 times per day, 30 days, A group of experimental rats with equal amount of saline instead of traditional gastric lavage. After dosing 27d excep