分子印迹微球用于去除雌激素污染物的研究-药物分析专业论文.docx

目 录 中文摘要······································································ 1 Abstract 3 前言 ······························································· 5 第一章 双酚 A 分子印迹聚合物微球的合成与性能评价 ··········· 7 1. 前言 ········································································ 7 2. 实验部分 ·································································· 7 3. 结果与讨论 ····························································· 11 4. 本章小结 ································································ 15 第二章 RP-HPLC 法同时测定水溶液中的六种酚类化合物 ······ 17 1. 前言 ······································································ 17 2. 实验部分 ································································ 17 3. 讨论 ······································································ 22 4. 本章小结 ································································ 22 第三章 BPA-MIPMs 用于去除水中的酚类雌激素污染物 ········· 23 1. 前言 ······································································ 23 2. 实验部分 ································································ 24 3. 结果与讨论 ····························································· 27 4. 本章小结 ································································ 38 全文总结···································································· 39 参考文献···································································· 41 综述·········································································· 49 致谢·········································································· 66 附录 1（攻读学位期间发表论文目录） ······························ 67 附录 2（图表）···························································· 68 华中科技大学硕士学位论文 华 中 科 技 大 学 硕 士 学 位 论 文 PAGE 1 PAGE 1 中 文 摘 要 环境内分泌干扰物是指可以干扰人或动物正常的内分泌功能，造成人或动物性别 改变或发育畸形的一大类物质。环境雌激素是环境内分泌干扰物中最重要的一类物质 之一。此类化合物结构稳定，生物降解能力弱，所以目前环境雌激素污染物的处理仍 缺乏有效的方法。 分子印迹技术是制备对某一特定分子具有选择性识别能力的聚合物的技术。分子 印迹聚合物具有构效预订性、特异识别性、广泛实用性等特点，目前在临床药物分析、 环境分析等许多领域均得到广泛应用。 本文以环境雌激素中的双酚 A（bisphenol A，BPA）为代表分子，利用沉淀聚合 法，合成 BPA 分子印迹微球（BPA-MIPMs），并以 BP