研究生学位论文：补阳还五汤联合激光在糖尿病性视网膜病变治疗中对内皮素-1的调控作用.doc

硕士学位论文 PAGE PAGE 1 分类号：R276.1 单位代码：10393 学 号 福建中医学院2007届硕士研究生 MASTERS DEGREE GRADUATE STUDENT OF FCTCM, 2007S 学位论文 ******************* ****************** MASTERS THESIS 补阳还五汤联合激光在糖尿病性视网膜病变治疗中对内皮素-1的调控作用 Effects of Buyanghuanwu decoction combined with Laser Photocoagulation on Endothelin 1 in patiens with Diabetic Retinopathy 专 业: 中医五官科学眼科方向 研究生: 朱 锐 导 师: 林 颖 主任医师 副教授 二00七年五月 中国·福州 目 录 CONTENT 中文摘要 ABSTRACT IN CHINESE···········································1 英文摘要 ABSTRACT IN ENGLISH···········································3 正文 CONTEXT··························································5 前言 INTRODUCTION·················································5 资料与方法 MATERALS AND METHODS·······································7 结果 RESULTS······················································13 讨论 DISCULTS······················································17 结论 CONCLUSION··················································24 参考文献 RENFERENCES···················································· 25 致谢 ACKNOWLEDGEMENT·············································29 附录 APPENDIXES······················································30 综述···························································30 补阳还五汤联合激光在糖尿病性视网膜病变治疗中对内皮素-1的调控作用 专 业: 中医五官科学眼科方向 方 向: 眼底病的中医临床研究 研究生: 朱 锐 导 师: 林 颖 主任医师 副教授 摘 要 目的：观察补阳还五汤加减联合激光在糖尿病性视网膜病变治疗中对内皮素-1的调控作用与延缓糖尿病性视网膜病变的发展及疗效的关系，探讨糖尿病性视网膜病变预防和治疗的新思路和新途径。 方法：对糖尿病性视网膜病变单纯型患者20例40只眼，糖尿病性视网膜病变增殖型患者20例34只眼，应用补阳还五汤加减配合视网膜光凝，观察治疗前后内皮素-1水平变化及临床疗效。 结果：（1）治疗两个月后单纯型组与增殖型组内皮素-1水平明显降低，与治疗前比较有非常显著性差异（P＜0.01，P＜0.01）。（2）治疗两个月后单纯型组内皮素-1水平与健康体检者比较无显著性差异（P＞0.05）,增殖型组与健康体检者比较有显著性差异（P＜0.05）。（3）治疗一个月后单纯型组与增殖型组视网膜出血及渗出（硬性渗出和棉绒