瑞芬太尼复合异丙酚阿曲库胺在鼻内窥镜围手术期应用比较.doc

瑞芬太尼复合异丙酚-阿曲库胺在鼻内窥镜围手术期应用比 蔡静杏高晓英黄晓光蔡昊(广东潮州市屮心医院麻醉科广东潮州521000) 屮图分类号】R765.9 】A 】1672-5085 (2012) 20-0111-02 】A的探讨鼻内窥镜术屮复合异丙酚-阿曲库胺全静脉麻醉时瑞芬太尼对 围手术期的影响。方法将76例鼻腔内窥镜手术复合异丙酚-阿曲库胺全静脉麻 醉患者，采用单盲随机设计，随机分为实验组(R组，n=36)和对照组(F组， n=36)o实验组采用瑞芬太尼先lmu;gmiddot;kg静推，继之以 12mu;gmiddot;kgmiddot;h静脉微泵输注。对照组采用芬太尼 3mu;gmiddot;kg 静推，继之以 2mu;gmiddot;kgmiddot;h 静脉微泉输注。 比较2组患者围手术期的变化。结果2组患者一般情况比较，P0.05,无统计 学差异。R组平均意识消失时间约为(87plusmn;11.6) s, F组平均消失时间 (132plusmn;10.3) s； R组围手术期血流动力学反应较F组更稳定；R组清醒 时间(209.6plusmn;30.1) s、拔管时间(275.7plusmn;21.4),较 F 组短，经比 较，P0.05,有统计学差异。结论瑞芬太尼复合异丙酚-阿曲库胺起效迅速， 恢复快，血流动力学反应稳定。 关键词】鼻A镜手术瑞芬太尼围手术期反应 Remifentanil and propofol ndash; Tracrium in endoscopic sinus Perioperative Abstract】 Objectives Nasal endoscope combined withpropofol -Tracrium for total intravenous anesthesia of remifentanil on peri operation period effect.Methods 76 cases of nasal endoscopy operation combined withpropofol -Tracrium total intravenous anesthesia patients,using a single blind randomized design,were randomly divided into experimental group(group R,n=36) and control group(group F,n=36).The experimental group using remifentanil tolmu;gmiddot;kg,followed byl2mu;gmiddot;kg middot;hintravenous micro pump infusion.The control group using fentanyl 3mu;gmiddot;kg,followed by 2mu;gmiddot;kg middot;hintravenous micro pump infusion.Note compared 2 groups of patients during operation period of.Results 2 groups of patients in general comparison,P gt; 0.05,no statistically significant differences.R group mean loss of consciousness about (87plusmn;11.6) s,F group mean extinction time of (132plusmn;10.3) s; R group during the operation period ofhemodynamic reSPOnse to a F is more stable; R group awake time (209.6plusmn;30.1) s,extubation time (275.7plusmn;21.4),shorter than that of F group.Comparatively,Plt;0.05,withstatistical difference.Conclusions Remifentanil combined withpropofol -Tracrium and quick,quick recovery,hemodynamic reSPOnse stability. Key words】 Nasal endoscopic operation Remifentanil Per