Flapfree LASEK和Flafree Epi.LASIK治疗中 低度近视临床效果比较.docx

优秀毕业论文 精品参考文献资料 Flap． Flap．free LASEK和Flap—free Epi．LASIK治疗中低度近视临床效果 比较 摘 要 目的比较去上皮瓣的准分子激光上皮瓣下角膜磨镶术(Flap—free LASEK)和去 上皮瓣的机械法准分子激光角膜上皮辨下磨镶术(Flap—free Epi．LASIK)治疗中、 低度近视的临床效果。 方法将78位患者143只眼(一1．50D～-6．OOD)，随机分为两组A组和B组，A组行 Flap—free LASEK术式，B组行Flap-free Epi．LASIK术式。观察术后眼球疼痛症状、 角膜上皮愈合时间和术后l、3、6个月裸眼视力及haze情况。 结果A、B两组术后3天眼球疼痛刺激症状l、2、3级例数的差异无统计学意义。A 组平均角膜上皮愈合时间为3．81±O．07天，B组平均为4．15±0．12天，两者差异有统计 学意义(t=2．42，PO．05)，术后l、3、6个月时视力和haze两组比较无统计学意义。 结论Flap—free LASEK矫正中、低度近视与Flap—free Epi．LASIK}ff比较，角膜上 皮愈合更快，术后疼痛刺激、视力恢复和haze的形成二者无明显差异。 硕士研究生许梅(病理生理学) 指导教师于小玲副教授 关键词 近视，Flap—free LASEK，Flap—free Epi．LASIK Clinical Clinical evaluation of Flap—free LASEK and Flap-free Epi．LASIK on the treatment of moderate and low myopia Abstract Objective To contrast the clinical efficacy of Flap-free LASEK and Flap—free Epi． LASIK for low and moderate myopia． Methods Seventy eight patients with 143 eyes(-1．50D--6．00D)were divided randomly into two groups．All subjective pain scores were evaluated on the third postoperative day． The days of corneal epithelium healing were recorded．The Uncorrected visual acuity(UCVA) and haze scores were detected in 1，3，6 months after surgery． Results Scores of pain WaS 110 obvious difference in group A and B on the third day postoperatively，while the day of corneal healing WaS significant difference in group A and B (仁2．42．PO．05)．The average day of epithelium well reconstruction WaS shorter in the group of the A(3．81士0．07)，and longer in group B(4．154-0．12)．The difference of the UCVA and haze scores were no statistical significance in 1,3，6 months after surgery between the two groups． Conclusion．The cornea epithelium well reconstruction WaS faster in Flap—free LASEK than that in Flap．free Epi．LASIK．There was no obviously difference in pain score，UCVA and haze score between the two groups． Postgraduate student：Xu Mei(Pathophysiology) Directed by：Associate Prof．Yu Xiao—Ling Key Words：Myopia；flap—free lasek：flap-free epi．1asi 引 引 青 引言 广泛开展的准分子激光角膜屈光手术在我国开展已经有近20年的历