抗菌药物相互作用.ppt

* budesonide 布地缩松 * Sucrose：蔗糖；Hydrolysis:水解；acetylation：乙酰化； arylsulfatase：芳香基硫酸酯酶；catechol ：邻苯二酚； Glacial acetic acid：冰醋酸 Sodium hydroxide (to adjust pH)；Fructose：果糖；Polysorbate 80：聚山梨醇酯 ；Tartaric acid：酒石酸；Hydrochloric acid：盐酸；Lactose monohydrate：一水乳糖；Citric acid (to adjust pH)：柠檬酸 * Source A (WPC), p 4, §X, ?2 1/Mycamine, p 1, C2, ?8,9 2/Eraxis, p 5, ?2 Source A (WPC), p 4, §X, ?2 1/Mycamine, p 1, C2, ?8,9 2/Eraxis, p 5, ?2, L1-5 Source A (WPC), p 4, §X, ?2 1/Mycamine, p 1, C2, ?8,9 2/Eraxis, p 5, ?2 Source A (WPC), p 3, §V, ?1 Source A (WPC), p 4, §X, ?2 2/Eraxis PI, p 5, ?2 Source A (WPC), p 3, §IV (by omission), §V, ?1, L17-18 References Mycamine? (micafungin sodium) For Injection. US Prescribing Information, Astellas Pharma US, Inc., June 2006. Eraxis? (anidulafungin) For Injection. US Prescribing Information, Roerig Division of Pfizer Inc, February 2007. Cyclosporine：环孢霉素； Tacrolimus：它克莫司；Nifedipine：硝苯地平； Sirolimus ：西罗莫司 ； anesthetics：麻醉剂 IVZ 2008-W-1259216-SS MS* Reference Goldstein EJC, Citron DM, Peraino V, et al. Introduction of 厄他培南 onto a hospital formulary: effect on antimicrobial usage and the in vitro 敏感性 on aerobic, 革兰阴性 rods. Poster presented at: 44th Annual Meeting of the 美国感染性疾病协会 (IDSA); 12–15 October 2006; Toronto, Ontario, Canada. NEW IVZ 2008-W-1259216-SS MS* In general, the more complex a patient’s drug regimen, the higher the risk for interactions. CKD patients often take numerous medications. The average age of a dialysis patient is over 60 years and as a group, elderly patients are more prone to experience drug interactions because of reduced hepatic and renal function. Identification of the potential for interactions may enable the clinician to avoid its occurrence. Drugs that require careful dose titration to maintain efficacy and avoid toxicity must be monitored particularly carefully for drug interactions. Reference Goldstein EJC, Citron DM, Peraino V, et al. Introduction of 厄他培南 ont