膳食纤维与体重控制.pptVIP

张爱珍 zhang Aizhen 浙江大学城市学院医学与生命科学学院 膳食纤维与体重控制 Dietary fiber and weight management 膳食纤维与体重控制 Dietary fiber and weight management 膳食纤维摄入量与体重、体脂呈负相关 Most but not all observational studies showed an inverse, sometimes dose-dependent relationship between DF consumption and body weight 水溶性膳食纤维和非水溶性膳食纤维 富含膳食纤维的天然食物和膳食纤维制剂 Generally, in human studies, no clear difference regarding weight gain has been shown between soluble and insoluble DF and fermentable and nonfermentable DF, or between foods naturally high in DF and fiber supplements Epidemiologic support that DF intake prevents obesity is strong 对体重控制效果类似 膳食纤维与体重控制 Dietary fiber and weight management 膳食纤维控制体重的可能机制 1 含亲水基团，吸水膨胀性 饱腹感 2 粘性、吸附性 延缓饥饿感 3 4 减少营养素吸收 5 改变肠道激素分泌 在大肠内发酵代谢 提供能量较少 Intervention studies： the addition of dietary fiber generally decreases food intake and, hence, body weight. Mechanisms： Inducing greater satiation and satiety Decreasing absorption of macronutrients Altering secretion of gut hormones Decreasing in energy intake and body weight loss mechanisms 国外的研究：膳食纤维与体重控制 Dietary fiber and weight management Howarth et al:mean values for published studies indicate that consumption of an additional 14 g/day fiber for 2 days is associated with a 10% decrease in energy intake and body weight loss of 1.9 kg over 3.8 months mean energy intake in all studies was reduced to 82% by higher fiber intake in overweight/obese people versus 94% in lean people;body weight loss was 2.4 kg versus 0.8 kg Epidemiologic support that DF intake prevents obesity is strong 补充 DF 14g/d 能量摄入：减少10%（消瘦者：6% 肥胖/超重者：18%） 体重：减轻1.9kg（消瘦者：0.8kg 肥胖/超重者：2.4kg） 对超重/肥胖症患者减轻体重的效果优于健康体重者 obese individuals may exhibit a greater suppression of energy intake and body weight loss 实验各组大鼠体重的变化情况(g， ) 组别 实验前体重 第2周 第6周 空白对照组 203.5±8.5 264.4±19.7 367.7±29.4 高脂模型组 202.2±9.4 281.2±16.8☆☆ 401.7±33.2☆☆ MCP低剂量组 204.5±7.8