脑出血合并静脉血栓栓塞的预防和治疗.pdfVIP

·513· ·综述· 脑出血合并静脉血栓栓塞的预防和治疗 顾双双沙杜鹃张均 【摘要】 静脉血栓栓塞包括深静脉血栓形成和肺栓塞，是卒中后的常见并发症之一，同时也能 显著增高卒中患者病死率。卒中患者因肢体瘫痪、长期卧床和特异性高凝状态而成为血栓形成的高 危人群。预防措施主要包括物理和药物预防。临床研究证实，抗凝治疗对于预防缺血性卒中患者的静 脉血栓栓塞有效。然而，对于自发性脑出血患者而言，抗凝药是否可用以及如何应用仍未达成共识， 主要是考虑存在再出血或血肿扩大的风险。文章对近年来的相关文献进行了回顾，总结了脑出血患 者静脉血栓形成的预防和治疗研究进展。 【关键词】静脉血栓栓塞；静脉血栓形成；脑出血；肺栓塞；抗凝药 thmI曲oent胁lismin with Preventionandtreatmentofvenous patients intracranial hemorrhage Jun啦 Du-juan2，ZHANG GU站1幽乎shu锄91，SHA Medical DrumTower Medical College,theAffiliated HospitalofNanjing 。踟明即可Department，Clinical 210008．China：2 DrumTower Affd妇ed University．NanjingEmergencyDepaffmlmt．NanjingHospild．the Medical 210008，China HospitatofNanjingUniversitySchool,Nanjing author：ZHANG Corresponding Jun．Ema／／：g弘汜hmg@y嘲∞．tom．cn Venous veinthrombosismad one 【Abstractl deep entx，lism,is thro蛐lism,including pulmonary oftheCOrlffrlon after italso increasesthe in with complicationsstroke，andsignificantly mortalitypatients stroke．Becauseoflimb bed with rest，andspecifichypercoagAablestate，thepatients paralysis，prolonged strokebecomethe risk ofthrombosis．The and hi【gh rr麟u璐manlyPhy7sical population preventive including studieshaveconfn-medthat forthe ofv∞ous drugprevention．Clinical anticoagulationtherapy prevention iseffectivein with