课件：猪肺炎支原体的免疫时机及疫苗的选择.ppt

* SLIDE 1: TITLE SLIDE: Vaccine Adjuvants * SLIDE 2: These are the three major types of vaccine adjuvants used in veterinary vaccines. * SLIDE 3: Aluminum hydroxide based vaccines are less viscous (thick) and are relatively free from reactions. The immune response is relatively fast but short-lived. Strong stimulation of the cell-mediated immunity (CMI) is not a feature of aluminum hydroxide adjuvants. * SLIDE 4: Water-in-oil adjuvants can have problems with reactions and syringeability because of the high percentage of oil in the product. * SLIDE 5: Oil-in-water adjuvants have the advantages of being more syringeable and less reactive than water-in-oil adjuvants. ? * SLIDE 6: This chart lists some of the M. hyo vaccines and the adjuvant type. * SLIDE 7: Introducing M+Pac * SLIDE 8: self-explanatory * SLIDE 9: self-explanatory * SLIDE 10: Emunade is an emulsion of aluminum hydroxide and oil-in-water which gives the benefits of producing fast-acting and long-lasting immunity to mycoplasma. This adjuvant also helps stimulate strong CMI. * SLIDE 11: self-explanatory * SLIDE 12: explained in slide 11 * SLIDE 13: self-explanatory * SLIDE 14: explained in slide 13 * SLIDE 34: This slide serves to introduce the next section which is vaccination schedules. * SLIDE 35: It is common in production systems today to vaccinate later than was done in the past. In many cases M. hyo vaccination is done at ~ 6 weeks of age and followed by a booster at ~ 8-9 weeks of age. Later vaccination is done to avoid any issues with maternal antibody interference. Also, since we want to ensure that the duration of immunity lasts through the finishing period, vaccination is done at these later ages. * SLIDE 36: This slide and slide 37 illustrate some of the work we have done on maternal antibody interference with M. hyo. These studies should probably be covered in detail in an additional presentation. Taking these two slides alone do not provide enough context. * SLIDE 37: see above * SLIDE 38: