ECCMID 曲霉菌指南简介 慢性肺曲霉菌病感染.pptxVIP

2014 ESCMID曲霉菌病治疗指南-慢性肺曲霉病 2014 ESCMID Aspergillus Guideline-Chronic Pulmonary Aspergillosis Present by David W.Denning [United Kingdom] ECCMID 10th May 2015 in Barcelona ) 欧洲临床微生物与感染性疾病学会(ESCMID,European Society of Clinical Microbiology and Infectious Diseases) 滨州医学院附属烟台海港医院 急诊科 王功军 Present by David Denning ECCMID 10th May 2015 in Barcelona 慢性肺曲霉菌病-疾病分类 Chronic Pulmonary Aspergillosis - subsets 单发曲霉球 Simple/single Aspergilloma 曲霉肉芽肿病 Aspergillus nodule(s) 慢性空腔曲霉菌病/复杂曲霉球病 Chronic Cavitary Pulmonary Aspergillosis/Complex Aspergilloma (CCPA) 慢性纤维化肺曲霉菌病 Chronic Fibrosing Pulmonary Aspergillosis (CFPA) 亚急性侵袭性/半侵袭性/慢性坏死性肺曲霉菌病 Subacute invasive(SIA)/Semi-Invasive/Chronic Necrotizing Pulmonary Aspergillosis (CNPA) 注：真菌球（曲霉球）可出现在以上除曲霉菌肉芽肿之外的任意一种情况中 – fungal balls (aspergilloma) may be seen in any of these conditions, except Aspergillus nodule Present by David Denning ECCMID 10th May 2015 in Barcelona 慢性曲霉菌病临床表现分类 Clinical phenotypes of chronic Aspergillus spp diseases 单发曲霉球 Single/simple aspergilloma 慢性坏死性/亚急性肺曲霉菌病 Chronic necrotizing pulmonary aspergillosis (CNPA) or subacute Invasive aspergillosis (SAI) 慢性空腔性肺曲霉菌病 Chronic cavitary pulmonary aspergillosis (CCPA) 慢性纤维化肺曲霉菌病 Chronic fibrosing pulmonary aspergillosis (CFPA) 曲霉菌肉芽肿 Aspergillus nodule(s) Present by David Denning ECCMID 10th May 2015 in Barcelona 不同类型的慢性曲霉菌病 Different patterns of CPA 曲霉菌肉芽肿Aspergillus nodule(s) 单发曲霉球 Single/simple aspergilloma 慢性空腔性肺曲霉菌病 Chronic cavitary pulmonary aspergillosis (CCPA) 慢性纤维化肺曲霉菌病 Chronic fibrosing pulmonary aspergillosis (CFPA) 慢性肺曲霉菌病-诊断标准 Chronic Pulmonary Aspergillosis – Diagnostic criteria 需要满足以下条件： 1.1 CT影像学表现为肺部真菌球 或 胸腔内空腔，或支气管扩张 Characteristic CT appearance of a fungus ball in a pulmonary or pleural cavity, or dilated bronchus, + 1.2 任何与曲霉菌感染相关的直接或间接的微生物证据 Any direct or indirect microbiological evidence of Aspergillus infection (see below). , 或： 2.1 影像学特征持续表现为慢性肺曲霉菌病（包括空腔，胸膜增厚，严重的纤维化或肉芽肿） Radiological features consistent with chronic pulmonary aspergillosis