管状胃在减轻食管癌术后胃食管反流病中的临床研究-外科学(普胸外科)专业论文.docxVIP

华 华 中 科 技 大 学 硕 士 学 位 论 文 PAGE 2 PAGE 2 The influence of gastric tube reconstruction on gastroesophageal reflux after esophagectomy for esophageal carcinoma Department of Thoracic Surgery, Tongji Hospital，Tongji Medical College，Huazhong University of Science and Technology Candidate: Chen Wenshu Supervisor: Prof. Fu Xiangning Abstract Objective: To investigate the effects of gastroesophageal reflux with gastric tube reconstruction after esophagectomy for esophageal carcinoma. Methods: According to hospital admission order and different surgical procedures, 43 patients with esophageal carcinoma were randomly divided into gastric tube group (including 20 cases) and traditional surgical group (including 23 cases). Another 20 healthy examination adults were served as a control group. The control group and patients with esophageal carcinoma were respectively underwent 24-hour esophageal pH monitoring and pairwise comparisons were held among three groups. Results: There were no statistically significant differences among the three groups with the general clinical data (p0.05), including gender and age. There were also no statistically significant differences among the three groups with total time、upright time and supine time of pH monitoring after surgery(p0.05), excluding the three above factors on the impact of test results. It was revealed by intraesophageal 24-hour pH monitoring that the DeMeester total appraise score, frequency of regurgitation of gastric juice during the hour period，frequency of reflux episodes 5 min, the longest time of keeping reflux, total time with pH 4.00 and percentage of total time with pH 4.00 in the traditional surgical group in the gastric tube groupin the control group，there were statistically significant differences among the three groups(p0.05). Conclusion: Gastroesophageal reflux is found in both surgical groups after esophagectomy, however, compared with traditional surgery group, reflux in gastric tube group significantly reduce