粒子植入的手术导航系统的开发与精度测试-软件工程专业论文.docxVIP

第 第 PAGE IV 页 第 第 III 页 术前计划模块、器械模块以及导航模块。 第二，研究了粒子植入算法，实现了等剂量曲面的绘制。通过研 究几种已有算法的实现效果，本系统采用 AAPM 推荐的计算方法进 行等剂量曲面的计算。 第三，实现了肿瘤体积的自动计算算法。该算法采用任意多面体 的四面体剖分算法，从而解决了不规则多面体的体积计算。 第四，介绍并实现了导航系统中的其他关键技术：图像分割，医 学数据三维可视化，路径规划，手术配准，术中报警。这些技术与等 计量曲面绘制，肿瘤体积计算共同形成了一个完善的系统。 最后，为了验证系统的性能，描述了相关实验。通过对心脏，头 部，脊椎的 CT 数据的测试，本系统的等剂量曲面绘制平均误差达到 1.2±0.5mm，剂量率与理论的剂量率的误差在 5%以内，基本满足临 床需求。对分割肿瘤体积的测试，本系统的误差在 10%以内，证明了 该体积计算方法的有效性。 关键词：粒子植入外科手术 手术导航 等剂量曲面 分割 肿瘤体积 计算 DEVELOPMENT AND PRECISION TEST OF NAVIGATION SYSTEM FOR PARTICLE IMPLANTATION ABSTRACT Computer-assisted surgical navigation technology taking advantage of many kinds of medical images not only can help surgeon doing the preoperative plan and minimizing the wound, but also can bring the surgery high quality and convenience. Surgical navigation system of particle implantation is using surgical navigation technology to treat the cancer. The system can provide surgeons with more intuitive information. According to the information of patient tumor in the computer screen, surgeon can decide the amount of particles and the positions of them to finish the preoperative plan. This system can help doctors implant particle accurately in target region and distribute the equal- dose evenly, which leads to the minimal trauma to the normal tissue. The system has the following technical difficulties: the segmentation of tumor, the 3D visualization of tumor, rendering the equal-dose surface of particles, and calculating volume of irregular polyhedron tumor etc. The main contribution of this paper includes the following aspects: Firstly, we designed and implemented the surgical navigation system of particle implantation. We analyzed the system process and divided system into the following modules: the patient data module, segmentation reconstruction module, surgical planning module, equipment module and navigation module. Secondly, we studied the calculation of particle implantation and realized the equal-dose surface rendering. After studied the