自身抗体患者的红细胞输注：是否有效和安全，不增加溶血风险？（英文）.pdf

Original Article Transfusion Medicine Ann Lab Med 2015;35:436-444 /10.3343/alm.2036 ISSN 2234-3806 • eISSN 2234-3814 Red Blood Cell Transfusion in Patients With Autoantibodies: Is It Effective and Safe Without Increasing Hemolysis Risk? 1,2 3 4 Sang Hyuk Park, M.D. , Won-Ho Choe, M.D. , and Seog-Woon Kwon, M.D. 1 Department of Laboratory Medicine , Pusan National University School of Medicine, Pusan National University Hospital, Busan; Biomedical Research 2 3 Institute , Pusan National University Hospital, Busan; Department of Laboratory Medicine , Eulji Medical Center, Eulji University School of Medicine, Seoul; 4 Department of Laboratory Medicine , University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea Background: The therapeutic efficacy of red blood cell (RBC) transfusions in patients with Received: November 4, 2014 autoimmune hemolytic anemia (AIHA) is highly debated because of speculations on the Revision received: January 16, 2015 Accepted: April 23, 2015 increased risk of transfusion reactions; yet it is a suggested adjuvant therapy in anemic patients with life-threatening hypoxemia. In this study, we evaluated the safety and effi- Corresponding author: Seog-Woon Kwon Department of Laboratory Medicine, cacy of RBC transfusions in AIHA patients.