嗜酸细胞胃肠炎病例.pptVIP

As per the definition, patients with EGIDs and sustained blood eosinophilia exceeding 1500 cells/mm would have HES. Therefore, routine surveillance of the cardiorespiratory system is warranted,especially if the patients have extragastrointestinal manifestations. They suggested the following diagnostic criteria: (1) the presence of gastrointestinal symptoms, (2) biopsies showing eosinophilic infiltration of one or more areas of the gastrointestinal tract from esophagus to colon, or characteristic radiologic findings with peripheral eosinophilia, (3) no evidence of parasitic or extraintestinal disease. The gastrointestinal tract is the main nonhematopoietic organ where eosinophils reside in the healthy state. Eosinophils are normally present in the lamina propria, but the number of eosinophils regarded as pathological for various sites along the gastrointestinal tract is debated; the highest concentrations are found in the cecum and appendix. Within the gastrointestinal tract, In published reports, the most frequently affected organs were the small intestine and stomach. Many patients with EG have a history of seasonal allergies, food sensitivities, eczema, asthma, and atopy. Talley et al. reported a history of allergy in 20 of 40 patients with EG. The most common foods reported to be positive by SPT include common food allergens—peanuts, eggs, soy, cow milk, and wheat—in addition to beans, rye, and beef. HES is an idiopathic condition defined as marked peripheral eosinoilia exceeding 1500 cells/μl that persists for at leas 6 months; there is organ dysfunction. Target-organ damage mediated by eosinophils is highly variable mong patients, with involvement of skin, heart, lung, central and peripheral nervous systems in more than 50% of cases. therapeutic strategy. First, they recommended specifi allergy avoidance (airborne and dietary). If this failed to improve EGID pathology, then they recommended glucocorticoid therapy, first starting with topical delivery an