利用效用度挖掘核心药物及配伍规律-计算机科学与探索.pdf

周伟，王峰，王崇骏，等.利用效用度挖掘核心药物及配伍规律[J].计算机科学与探索，2013 ，7（11）：994-1001. ISSN 1673-9418 CODEN JKYTA8 E-mail: fcst@vip. 163.com Journal of Frontiers of Computer Science and Technology 1673-9418/2013/07(11)-0994-08 Tel: +86-10 doi: 10.3778/j.issn. 1673-9418.1305007 利用效用度挖掘核心药物及配伍规律* 1,2 1,2 1,2+ 1,2 周 伟 ，王 峰 ，王崇骏 ，谢俊元 1. 南京大学 计算机科学与技术系，南京 210023 2. 南京大学 软件新技术国家重点实验室，南京 210023 Mining Core Herbs and Their Combination Rules Using Effect Degree ZHOU Wei1,2 , WANG Feng1,2 , WANG Chongjun1,2+ , XIE Junyuan1,2 1. Department of Computer Science and Technology, Nanjing University, Nanjing 210023, China 2. State Key Laboratory for Novel Software Technology, Nanjing University, Nanjing 210023, China + Corresponding author: E-mail: chjwang@ ZHOU Wei, WANG Feng, WANG Chongjun, et al. Mining core herbs and their combination rules using effect degree. Journal of Frontiers of Computer Science and Technology, 2013, 7(11) ：994-1001. Abstract: Traditional Chinese medicine formula (TCMF) is a main treatment measure in traditional Chinese medicine (TCM). However, a formula always contains many herbs and only some herbs play an important role in the formula, so it ’s meaningful to find the core herbs and their combination rules. To solve the problem, this paper proposes an algorithm based on effect degree (ED) which includes three main steps. The three steps are core herbs discovery algorithm based on ED, network construct algorithm based on pointwise mutual information with herb pair ED (PMIED) and herb combination rules detection algorithm based on overlapping communities. Through experime