冠状动脉介入治疗对非ST段抬高型急性冠脉综合征并左心室功能不全患者心功能的影响.docx

冠状动脉介入治疗对非ST段抬高型急性冠脉综合征并左心 室功能不全患者心功能的影响 湖南省人民医院湖南长沙410005 【摘要】目的：探讨介入治疗对冠心病合并左心室功能不全心功能产 生的影响。方法选取我院2012年3月?2015年3月非ST段抬高急性冠脉综合征 的冠心病合并左心室功能不全患者106例，将其分为研究组与对照组各53例。 两组冠状动脉均为经冠脉造影证实含前降支近段的多支多处严重狭窄。研究组实 施介入治疗及药物治疗，对照组因患者意愿未行介入治疗而仅予以药物治疗，对 比两组NYHA心功能分级、左心室舒张末期内径（LVEDD）、收缩末期内径（LVESD）、 左心室射血分数（LVEF）及左心室短轴缩短率（LVFS）。结果治疗前两组患者的 左心室功能相关指标比较差异无统计学意义，治疗后两组患者的左心功能相关指 标均有改善，研究组患者左心室舒张末内径及左心室收缩末内径两项指标的下降 幅度较大，左室射血分数及左室短轴缩短率两项指标上升明显，与对照组比较, 差异有统计学意义（Plt;0. 05）o结论在药物治疗基础上，对于非ST段抬高型 急性冠脉综合征合并左心室功能不全患者，对包含前降支严重病变的冠脉介入治 疗可进一步改善心功能、抑制心室重塑。 【关键词】急性冠脉综合征；心功能不全；介入治疗：心功能 Abstract： Objective： To investigate the effect of interventional therapy on the left ventricular function in patients with coronary artery disease. Methods 106 patie nts with non ST segme nt elevati on acute cor on ary syn drome with non -2015 segment elevation acute coronary syndrome in our hospital from March 2012 to March were divided into study group and control group with 53 cases in each group. The two groups of cor on ary artery an giography con firmed that the proximal segme nt of the an terior descendi ng branch was much more severe tha n that of the cor on ary artery? The study group was treated with interventional therapy and drug treatment? The control group was treated with drugs, compared with two groups of NYHA heart function classification, left ventricular end diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), left ventricular ejection fraction (LVESD) and left ventricular short axis shortening rate (LVFS) ? Results there were no significant differences in left ventricular function in the two groups before treatment, and the left ventricular function in the two groups were improved. The left ventricular diastolic diameter and left ventricular end systolic diameter of the left ventricle were sign ifica ntly in creased, left ven tricular ejection fraction and left ven tricular short axis shorte ning rate of two in dicators in creased sign 讦 icantly compared with the control group (Plt;