老年(高龄)房颤患者的抗凝治疗策略.pptVIP

谢 谢！ Prevention of stroke in atrial fibrillation September 2007 * The problem of underutilisation of VKAs is greatest in the elderly. As the current slide shows, the percentage of patients eligible for treatemnt who received VKA therapy decreased from 61% in patients aged between 65 and 74 years to 35% in patients aged 85 years or above. Reference: Go AS, Hylek EM, Borowsky LH, Phillips KA, Selby JV, Singer DE. Warfarin use among ambulatory patients with nonvalvular atrial fibrillation: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. Ann Intern Med 1999;131:927-34. Prevention of stroke in atrial fibrillation September 2007 * The problem of underutilisation of VKAs is greatest in the elderly. As the current slide shows, the percentage of patients eligible for treatemnt who received VKA therapy decreased from 61% in patients aged between 65 and 74 years to 35% in patients aged 85 years or above. Reference: Go AS, Hylek EM, Borowsky LH, Phillips KA, Selby JV, Singer DE. Warfarin use among ambulatory patients with nonvalvular atrial fibrillation: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study. Ann Intern Med 1999;131:927-34. Increased prevalence of AF with advancing age: the ATRIA and Rotterdam studies The increased risk of AF in men and with ageing can be seen clearly when examining the findings of the ATRIA and Rotterdam studies.1,2 In the California-based ATRIA study, prevalence of AF was assessed in a population of 17,974 adults. The overall prevalence of AF was 1.1% in men compared with 0.8% in women(p0.001); this increased prevalence was seen across all age groups Prevalence also increased from 0.1% among adults aged 55 years to 9.0% in persons aged ≥80 years1 The Rotterdam study was a population-based prospective cohort study among subjects aged ≥55 years living in a suburb of Rotterdam, The Netherlands. In this particular analysis, the prevalence and incidence of AF in this populat