药学专论药物化学.pptxVIP

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药学专论药物化学.pptx

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参考书目：药物化学，尤启东，化学工业出版社药学概论，张德志，中国医药科技出版社天然产物全合成，李绍顺，化学工业出版社现代有机合成化学，吴毓林，科学出版社维谱网和医学数据库，关键词：海洋药物、组合化学、QSAR、生物信息学、天然产物化学与药物化学相关科研网站////SciFinder///Journal of America Chemistry Sociaty (JACS, IF=9.023)Journal of Medicine Chemistry (JMC, IF=5.027)Journal of Organic Chemistry (JOC, IF=4.002)Organic Letter (IF=5.252)Journal of Natural Products (JNP, IF=2.872)JACSJACSJACSJACSNOTE: JACS will consider Communications of any length up to 4 journal pages and will include the Abstract in the PDF and print versions. Authors should refer to the /paragonplus/submission/jacsat/jacsat_authguide.pdfAuthor Guidelines [PDF] and use the /page/jacsat/submission/jacsat_templates.htmlCommunications template when submitting Communications.JMCJ. M. C. J. M. C. Journal ScopeThe Journal of Medicinal Chemistry publishes studies that contribute to an understanding of the relationship between molecular structure and biological activity or mode of action.Journal StandingJournal of Medicinal Chemistry is the most-cited journal in Medicinal Chemistry with 52,858 total citations in 2010 and an Impact Factor of 5.207, ranking it also as the #1 primary research journal in impact in the category as reported in the 2010 Journal Citation Reports? (Thomson Reuters,2011).Some specific areas that are appropriate include the following:Design, synthesis, and biological evaluation of novel biologically active compounds, diagnostic agents, or labeled ligands employed as pharmacological tools. Molecular modifications of reported series that lead to a significantly improved understanding of their structure-activity relationships (SAR). Routine extensions of existing series that do not utilize novel chemical or biological approaches or do not add significantly to a basic understanding of the SAR of the series will normally not be accepted for publication.Structural biological studies (X-ray, NMR, etc.) of relevant ligands and targets with the aim of investigating molecular recognition processes in the action of b