病理学见习课课件：Circulation+Disorders+1.ppt

Hyperemia Congestion Hemorrhage Thrombus Objectives Keywords: hyperemia, hemorrhage, thrombus Recognize: the major morphologic changes of hyperemia and thrombi Understand: the mechanism of thrombosis Gross No.1 Chronic congestion of the liver (nutmeg liver) No.56 Chronic congestion of the spleen No.103 Chronic congestion of the lung No.2 Hyperemia of the meninges No.5 Cerebral hemorrhage No.6 Mixed thrombus of the vein No.35 Acute rheumatic endocarditis Slides No.1 Chronic congestion of the liver No.14 Chronic congestion of the lung No.93 Acute congestion of the lung No.7 tumor embolus in the lung No.6 Organization of the thrombus * * Circulation Disorders Part 1 Apperance of nutmeg Classical nutmeg pattern seen in the cut section of liver, typical of chronic passive congestion. This is often seen in chronic congestive failure. The red markings are due to congestion around the central veins of hepatic lobules. Gross 1 Chronic congestion of the liver (nutmeg liver) Chronic passive congestion of the liver secondary to cardiac insufficiency, the classic “nutmeg liver”. Gross 1 Chronic congestion of the liver (nutmeg liver) Slide 1 Chronic congestion of the liver Microscopically, the nutmeg pattern results from congestion around the central veins, as seen here. This is usually due to a right heart failure. Slide 1 Chronic congestion of the liver The central vein and peripheral hepatic sinusoids are full of RBC, which means congestion. Slide 1 Chronic congestion of the liver Slight fibrotic hyperplasia can be seen in the portal area. Slide 1 Chronic congestion of the liver Congestion of central vein centrilobular sinusoids. In some areas, bilirubin inclusions can be found in hepatocytes (cholestasis). Slide 1 Chronic congestion of the liver Slight degeneration of hepatocytes can be seen (what kind?) Slide 1 Chronic congestion of the liver What kind of degeneration can you seen? Gross 56 Chronic congestion of the spl