皮肤针加贴棉灸法治疗神经性皮炎的临床分析.docx

摘要 目的：本研究采用随机对照临床试验，探讨皮肤针加贴棉灸治疗神经性 皮炎的临床疗效。 方法:共110例病人纳入研究，并被随机分配进入治疗组和对照组。其 中剔除、脱失病例12例，98例病人完成了整个研究过程并纳入分析。治疗组 釆用皮肤针加贴棉灸法治疗，每2 口治疗1次；对照组采用中效激素类药物， 醋酸去炎松尿素软膏外涂，每日3次，两组均以4周为1疗程，每周观察一次 疗效并以数码相机拍摄记录皮损情况。以患者治疗前后的证候积分量表为疗效 评价标准，并对每周局部皮损情况予数码拍照。 结果：(1)两组的基线状况良好，分组均衡，可比性较强(P0. 05)o (2) 治疗组的显效率为(94. 00%),较对照组(72. 92%)有极显著性差异(Pv0.05)。 (3)治疗组的3、6月复发率明显低于对照组(P0. 05)o 纟吉论：(1)皮肤针加贴棉灸的方法能显著改善神经性皮炎症状。(2)皮肤针 加贴棉灸的方法不良反应极少，安全性好。(3)皮肤针加贴棉灸治疗神经性皮炎 的3、6月复发率明显低于对照组。 尖键词：皮肤针、贴棉灸、神经性皮炎、临床研究 ABSTRACT Objectives: A randomized method was used to observe the efficacy of dermal needle matching cotton moxibusting A-shi points for the treatment of neurodermitis. Methods: All 110 patients were divided into treatment group and control group randomly, 98 accomplished and 12 missing. Treatment group gave dermal needle matching cotton moxibusting in Ashi points，3 time a week and total 4 weeks. Control group treated with Triamcinolone and Urea Cream , 2 times a day for 4 weeks. Symptom-and-sign scale, Digital photograph, were used to evaluate the clinical efficacy. Results: (1) The level from baseline of the treatment group was similar to that of the control (P0.05). (2) The effective rate of treatment group was 94.00%, and the effective rate of the control group was 72.92%. There was significant defference between the two groups (P0.05). (3) The treatment group in 3 and 6 month recurrence was significantly lower than the control group. Conclusion: (1) dermal needle matching cotton moxibusting can obviously improve symptoms of neurodermitis. (2) dermal needle matched cotton moxibusting was safty in use. (3) The dermal needle matching cotton moxibusting group in 3 and 6 month recurrence was significantly lower than the control group. Key wards: dermal needle, Cotton Moxibustion, neurodermitis, RCT 缩略词表 缩略词 英文全称 中文全称 CRF Case report form 病例报告表 EBM Evidence-based medicine 循证医学随 RCT Randomized controlled trial 机对照试验 SOPs Standard operating procedures 标准操作程序 申明 硕士学位论文《皮肤针加贴棉灸法治疗神经性皮炎的临床研 究》是本人在成都中医药大学攻读硕士