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资料参考讲义遗传学遗传chapter06 dna structure replication and recombination.pdf

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Chapter 6 DNA Structure, Replication, and DNA Structure, Replication, and Recombination Recombination Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 6-1 Outline of Chapter 6 Outline of Chapter 6  How investigators pinpointed DNA as the genetic  How investigators pinpointed DNA as the genetic material material  The Watson-Crick model of DNA structure  The Watson-Crick model of DNA structure  How DNA replicates  How DNA replicates  How DNA recombines information  How DNA recombines information Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 6-2 How investigators pinpointed DNA as How investigators pinpointed DNA as the genetic material? the genetic material? Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 6-3 Discovery of DNA Discovery of DNA  1869 – Friedrich  1869 – Friedrich Miescher extracted a Miescher extracted a weakly acidic, weakly acidic, phosphorous-rich phosphorous-rich material from nuclei material from nuclei of human white blood of human white blood cells which he named cells which he named nuclein. nuclein. Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 6-4  DNA – deoxyr nucleic  DNA – deoxyr nucleic acid acid Four nucleotide subunits  Four nucleotide subunits linked together by linked together by phosphodiester bonds. phosphodiester bonds. Nitrogenous Base Fig. 6.2 Copyright © The McGraw-Hill Companies, Inc. Permission required to reproduce or display 6-5 What Are Genes Composed of ?