心血管病传统及新危险因素评价.ppt

结论 心血管疾病在全球范围内高发病率和死亡率 心血管疾病是渐进的，通过各种传统和新危险因素，其高风险和事件序贯而至。 诸如下列药物等措施可有效的处理CV高危患者，可以减少心血管事件的风险。 他汀类药物 抗血小板制剂 控制血糖抗高血压药 β-阻断剂 RAS阻滞剂 * * Cardiovascular disease (ischaemic heart disease and cerebrovascular disease) is projected to account for 24% (13.4% and 10.4%, respectively) of total deaths worldwide by 2030, and ischaemic heart disease to account for 4.7% of disability-adjusted life years.1 Although there have been some improvements in morbidity and mortality statistics in some countries over the past few decades (e.g. the decline of coronary artery disease in the USA), atherosclerotic CVD remains the leading cause of morbid events and death worldwide, and it will become increasingly dominant in developing countries over the coming years as lifestyle and dietary changes occur.1,2 The consequences of a first CV event (i.e. MI, stroke, heart failure) are profound,3 not only for the patient and his/her environment, but also with regard to health economics issues. References: Mathers CD, Loncar D, 2006 Projections of Global Mortality and Burden of Disease from 2002 to 2030. PLoS Med 3(11): e442. Ezzati M. Estimates of global and regional potential health gains from reducing multiple major risk factors. Lancet 2003;362:271–80. Yach D, et al. The global burden of chronic diseases: overcoming impediments to prevention and control. JAMA 2004;291:2616–20. * Cardiovascular disease is a major healthcare problem not only high income nations but also in the Middle East, eastern Europe and Asia. According to the World Health Organization, cardiovascular disease accounted for around 30% of all deaths in 2005 (i.e. 17 million deaths).1 Heart disease (coronary artery disease or ischaemic heart disease) is the leading cause of death globally. Stroke is the other major cause of cardiovascular death. In Europe, coronary heart disease accounts for 40% of CVD deaths and cerebrovascular disease accounts for 25%.2 Reference: WHO 2005. Preventing Chronic Diseases: a Vita