乳腺化生性癌.pptx

乳腺化生性癌;Metaplastic breast carcinoma（MBC）;WHO乳腺肿瘤组织学分类标准;Wargotz and Norris分类;低级别腺鳞癌;纤维瘤病样化生性癌;鳞状细胞癌;梭形细胞癌;伴间叶分化的癌;肌上皮癌;9、 人的价值，在招收诱惑的一瞬间被决定。六月-21六月-21Tuesday, June 01, 2021 10、低头要有勇气，抬头要有低气。20:56:3820:56:3820:566/1/2021 8:56:38 PM 11、人总是珍惜为得到。六月-2120:56:3820:56Jun-2101-Jun-21 12、人乱于心，不宽余请。20:56:3820:56:3820:56Tuesday, June 01, 2021 13、生气是拿别人做错的事来惩罚自己。六月-21六月-2120:56:3820:56:38June 01, 2021 14、抱最大的希望，作最大的努力。01 六月 20218:56:38 下午20:56:38六月-21 15、一个人炫耀什么，说明他内心缺少什么。。六月 218:56 下午六月-2120:56June 01, 2021 16、业余生活要有意义，不要越轨。2021/6/1 20:56:3820:56:3801 June 2021 17、一个人即使已登上顶峰，也仍要自强不息。8:56:38 下午8:56 下午20:56:38六月-21;Cut off;发病机制;临床病理特征;Nelson, R.A., et al., Survival outcomes of metaplastic breast cancer patients: results from a US population-based analysis. Ann Surg Oncol, 2015. 22(1): p. 24-31. ;Schroeder, M.C., et al., Early and Locally Advanced Metaplastic Breast Cancer: Presentation and Survival by Receptor Status in Surveillance, Epidemiology, and End Results (SEER) 2010-2014. Oncologist, 2018. ;Rakha, E.A., et al., Prognostic factors in metaplastic carcinoma of the breast: a multi-institutional study. Br J Cancer, 2015. 112(2): p. 283-9. 肖盟等, 乳腺化生性癌的临床病理特征及预后影响因素. 中国肿瘤临床, 2015(12): 第614-619页 ;Nelson, R.A., et al., Survival outcomes of metaplastic breast cancer patients: results from a US population-based analysis. Ann Surg Oncol, 2015. 22(1): p. 24-31. ;治疗方式;化疗;化疗;靶向治疗;Schroeder, M.C., et al., Early and Locally Advanced Metaplastic Breast Cancer: Presentation and Survival by Receptor Status in Surveillance, Epidemiology, and End Results (SEER) 2010-2014. Oncologist, 2018. ;PI3K-AKT-mTOR通路抑制;Basho, R.K., et al., Targeting the PI3K/AKT/mTOR Pathway for the Treatment of Mesenchymal Triple-Negative Breast Cancer: Evidence From a Phase 1 Trial of mTOR Inhibition in Combination With Liposomal Doxorubicin and Bevacizumab. JAMA Oncol, 2017. 3(4): p. 509-515.;免疫抑制（ PD1/PD-L1 ）;放疗;Tseng, W.H. and S.R. Martinez, Metaplastic breast cancer: to radiate or not to radiate? Ann Surg Oncol