（英）甲醛对新生辣椒素治疗致特应性皮炎模型的影响.pdfVIP

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（英）甲醛对新生辣椒素治疗致特应性皮炎模型的影响.pdf

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Journal of Visualized Experiments Video Article Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin reatment 1 2 1 1 3 1 Rafael Taeho Han , Seung Keun Back , JaeHee Lee , Hye young Kim , Hee Jin Kim , Heung Sik Na 1 Neuroscience Research nstitute Department of Physiology, College of Medicine, Korea University 2 Department of Pharmaceutics and Biotechnology, College of Medical Engineering, Konyang University 3 Division of Biological Science and Technology, Science and Technology College, Yonsei University Wonj u Campus Correspondence to: Heung Sik Na at hsna@korea.ac.kr URL: /video/55987 DOI: doi:10.3791/55987 Keywords: mmunology, ssue 127, Formaldehyde, exposure, air pollutant, atopic dermatitis, capsaicin, animal model Date Published: 9/27/2017 Citation: Han, R.T., Back, S.K., Lee, J., Kim, H.y., Kim, H.J., Na, H.S. Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis nduced by Neonatal Capsaicin Treatment. J. Vis. Exp. (127), e55987, doi:10.3791/55987 (2017). Abstract Atopic dermatitis is chronically relapsing pruritic eczema and prevails around the world especially in developed countries. Complex interactions between genetic and environmental factors are known to play an important role in the pathophysiology of atopic dermatitis. However, we still lack a detailed picture of the pathogenesis of this disease. Thus, it is of importance to develop appropriate animal models for elucidating the progression of atopic dermatitis. Moreover, investigating the effect of environmental factors such as air pollutants on atopic dermatitis expands understanding of the disease. Here, we describe a method f