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COMMENTARY
Improving the Reporting Quality of Nonrandomized Evaluations
of Behavioral and Public Health Interventions:
The TREND Statement
Developing an evidence base | Don C. Des Jarlais, PhD, Cynthia Lyles, PhD, Nicole Crepaz, PhD, and the TREND Group
for making public health deci-
sions will require using data
from evaluation studies with
OVER THE PAST SEVERAL Also in this issue, Donner and Furthermore, evidence-based
randomized and nonrandom- 7 8
decades, a strong movement to- Klar, Murray et al., and Var- practice may often rely on meta-
ized designs. Assessing indi- 9
ward evidence-based medicine nell et al. provide overviews of analyses of large numbers of
vidual studies and using stud- 1–3
has emerged. In the context of the benefits and pitfalls of the studies, some of which may re-
ies in quantitative research
syntheses require transparent evidence-based medicine, clinical group-randomized trial, which, port negative results. Meta-
reporting of the study, with suf- decisions are based on the best in some situations, may be a analysis requires full reporting
ficient detail and clarity to read- available scientific data rather reasonable alternative to the of methods and outcomes to en-
ily see differences and similar- than on customary practices or
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