讲义文稿成果star文章类优化fluid1.pptx

modeFRONTIER Users Meeting 2006September, 28thApplication of Multi Objective Genetics Algorithm (MOGA) to Design and Development of an Artificial OrgansIchiro TAGA 1, Akio FUNAKUBO 2, and Yasuhiro FUKUI 2 1 Kawasumi Laboratories2 Department of Electronics and Computer Engineering, Tokyo Denki Universityheartreservoirvenous reservepumpBlood circulationArtificial lunggas exchangeOpen Heart Surgeryvenous drainagearterial infusionArtificial LungImportance of Flow Visualization StudyIn the artificial lung, bloodstream shows a complex flow pattern in order to flow through the outside of fiber membrane. Stagnation and Channeling usually occurred due to the difference of artificial lung design (housing geometry and shape of fiber bundle). Channeling Gas Exchange Performance deterioration Stagnation Thrombus FormationThe performance of artificial lung largely depends on blood flow.Computational Fluid Dynamics (CFD)MENOX 4000EL Analysis conditionsDensity of the hollow fiber membrane 45%Blood contact surface condition Non-slipperyOutlet flow condition Free from pressureInlet flow rate 3 L/minGravitation force From outlet to inletFluid type Newtonian fluidViscosity of blood 3.3 cP (0.0033 Pa?s)Density of blood 1060kg/m3Boundary conditions Nonslip CFD modelFlow of the Porous MediaFiber bundle was defined as porous mediaIt is difficult to model fiber bundle with a complex structure on a computer. Governing equationThe porous media permeability was calculated by applying to Darcys law (1) and Ergun’s equation (2).(1)(2)Where p is the pressure, Ki is the permeability coefficient of porous media, ui is fluid velocity, Dp is the outer diameter of hollow fiber, is the void fraction, Po is the inlet pressure,