课堂的磁力来自哪里？---浅谈驾驭课堂的动力与能力.ppt

M. Nirenberg P. Leder (1964. Science 145;1399) In vitro tRNAaa Ribosome Nitrocellulose filter UCU (trinucleotides) Ser-C14, Leu, Lys, Arg,… Ser, Leu-C14, Lys, Arg,… Ser, Leu, Lys-C14, Arg,… …… The biogenesis of miRNA Review: Geogre S Mack, Nature Biotech., 2007 The biogenesis of miRNA Review: Geogre S Mack, Nature Biotech., 2007 The biogenesis of miRNA Review: Geogre S Mack, Nature Biotech., 2007 The biogenesis of miRNA Review: Geogre S Mack, Nature Biotech., 2007 The biogenesis of miRNA Review: Geogre S Mack, Nature Biotech., 2007 The biogenesis of miRNA Review: Geogre S Mack, Nature Biotech., 2007 The biogenesis of miRNA Review: Geogre S Mack, Nature Biotech., 2007 Epigenetics and Molecular Mechanism 生命科学技术学院 郑用琏 for their discovery of RNA interference - gene silencing by double-stranded RNA. NP 2006 Craig C. Mello 马萨诸塞州医学院 Andrew Z. Fire, 斯坦福大学医学院 6.2.2.2.1 RNA interference (RNAi )的发现与证实 Double-stranded RNA-induced RNA Interference causes destruction of a specific mRNA Fire, Andrew. et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391 (1998) f. 3, p, 809 injected dsRNA of C. elegans mex-3 mRNA into C. elegans ovaries after 24 h, fixed ovaries and hybridization with probe ( mex-3 mRNA) No probe -ck No injection +ck Injection antisense RNA Some mRNA Injection dsRNA No detectedmRNA RNA interference Gene silencing by D.S RNA 郑 用 琏 华中农业大学生命科学技术学院 作物遗传改良国家重点实验室 Take every effort Make good PowerPoint Take every effort Make good PowerPoint 讲述概念 提炼要义, 实验佐证 重在分析; 力求全面 突出重点, 双语教学 强化记忆; 哈佛大学校长谈哈佛特点: 哈佛大学校长谈哈佛特点: 学生从教师从课堂中学到的知识=40% 学生自学和从同学中学到的知识=60% 哈佛大学校长谈哈佛特点: 学生从教师从课堂中学到的知识=40% 学生自学和从同学中学到的知识=60% 基本概念 + 逻辑分析 哈佛大学校长谈哈佛特点: 学生从教师从课堂中学到的知识=40% 学生自学和从同学中学到的知识=60% 基本概念 + 逻辑分析 分析他人论文！ 如何发现问题？ 如何设计实验？ 如何分析问题？ 如何解决问题