循证治疗专题知识讲座.ppt

循证诊疗专题知识讲座;关键内容;关键性;关键性;关键性;关键性;例1: ;实际上;例2;随机对照临床试验得到了未曾预料 结果（ED Stein AE,et al.J Am Coll Cardiol,1991,18:14）: ;提醒说明;关键内容;诊疗性研究证据 分级;关键内容;Case;;question;;;;评价证据（ctitical appraisal） 基础内容;;;1、Was the assignment of patients to treatment randomized? ;;本研究实际情况: ;2、Was the randomization concealed? ;;3、Were the groups similar at the start of the trial? ;本研究实际情况: ;4、Was follow-up of patients sufficiently long and complete? ;;;本研究实际情况: ;5、were all patients analyzed in the groups to which they were? ;;冠心病手术与药品诊疗情况比较;A.效力分析（efficacy analysis）;;冠心病手术与药品诊疗效力分析;B.实际诊疗分析（treatment received analysis）或解释试验（Expianatory trials）分析;冠心病手术与药品诊疗实际诊疗分析;;C.意愿诊疗分析（intension-to-treat analysis,ITT）;;冠心病手术与药品诊疗实际诊疗分析;;;冠心病手术与药品诊疗三种诊疗分析方法;;本研究实际情况: ;6、Were patients, clinicians, and study personnel kept blind to treatment? ;;本研究实际情况: ;7、Were groups treated equally, apart from the experimental therapy? ;本研究实际情况: ;;1、What is the magnitude of the treatment effect? ;;;;;;2、How precise is this estimate of the treatment effect？;;;1、is our patient so different from those in the study that its result cannot apply? ;本研究结果;;;4、What are our patient’s values and expectations for both the outcome we are trying to prevent and the treatment we are offering? ;;;;