大鼠和小鼠辨证论治标准的建立和用途.doc

大鼠和小鼠辨证论治标准的建立和用途 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：大鼠和小鼠辨证论治标准的建立和用途 1 1 大鼠和小鼠辨证论治标准的建立 3 2 大鼠和小鼠辨证论治标准的用途 6 文2：大鼠和小鼠辨证论治标准的建立和用途 9 1 大鼠和小鼠辨证论治标准的建立 11 2 大鼠和小鼠辨证论治标准的用途 14 参考文摘引言： 17 原创性声明（模板） 18 文章致谢（模板） 19 正文 大鼠和小鼠辨证论治标准的建立和用途 文1：大鼠和小鼠辨证论治标准的建立和用途 Abstract: Methodology of syndrome differentiation and syndromebased treatment in rats and mice has professional characteristics and cate to the research and development of traditional Chinese medicine (TCM). In this paper, the autho introduced their systematic research in five aspects. 1) Rats and mice can be used to simulate TCM clinical practice. Diagnosis and syndrome differentiation can be done to the rats and mice, and information collected by the four diagnostic methods from the experimental animals meets the requirements of treatment based on syndrome differentiation. 2) Standardized and quantified four diagnostic methods and syndrome differentiation for rats and mice can be established, and are operational and applicable for general use. 3) There exists cotitution and syndrome diveity in normal rats and mice. A spontaneous syndrome can develop in diseased rats and mice, and it can be accompanied by or even change to another syndrome, similar to that in human beings. 4) There is a complicated material base for syndromes inferred from the different gene expressio and splices in neuroendocrineimmune network. 5) Individualized treatment based on syndrome differentiation, as well as quantified evaluation and comparison of the treatment efficacy can be done in the rat and mouse models of syndromes. The established methodology and criteria for syndrome differentiation and syndromebased treatment in rats and mice can be used in the following four research fields: 1) syndrome identification on rat or mouse models; 2) research on the basic theories of TCM, such as the research on the viscera manifestation theory, the material base of syndromes, function mechanisms of the treatment ba