BIS用于经鼻蝶垂体瘤切除术指导异氟烷吸入对麻醉恢复的影响临床医学.doc

BIS用于经鼻蝶垂体瘤切除术指导异氟烷吸入对麻醉恢复的影响临床医学 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：BIS用于经鼻蝶垂体瘤切除术指导异氟烷吸入对麻醉恢复的影响临床医学 1 1 资料与方法 3 2 结果 4 3 讨论 5 文2：经鼻蝶垂体瘤切除术疗效分析 6 1 资料与方法 6 2 结果 8 3 讨论 8 参考文摘引言： 9 原创性声明（模板） 10 文章致谢（模板） 11 正文 BIS用于经鼻蝶垂体瘤切除术指导异氟烷吸入对麻醉恢复的影响临床医学 文1：BIS用于经鼻蝶垂体瘤切除术指导异氟烷吸入对麻醉恢复的影响临床医学 Abstract： Objective To explore the effect of using bispectral index (BIS) in titration of isoflurane to improve early recovery of patients undergoing microscopic traphenoid surgery for pituitary adenoma. Methods Thirty ASA Ⅰ-Ⅱpatients, aged from 18 to 65 yea old, undergoing microscopic traphenoid surgery for pituitary adenoma were randomly divided into two groups (n=15 each): BIS group and control group. Before induction, BIS seor was applied to the forehead and connected to Aspect A2000XP BIS monitor. All patients received standard anesthetic induction drugs，and %-3% isoflurane inhalation and standard remifentanil continuing infusion with micropump was used for maintenance of anesthesia. In the BIS group, the concentration of isoflurane was titrated to keep BIS at 40-60 level during the operation. In the control group, the anesthesiologist was blinded to BIS, and the concentration of isoflurane was changed according to the patients’ hemodynamic changes. The hemodynamic data, BIS values, and iso?urane concentratio were recorded every 5 minutes during operation. At the end of the study, recovery criteria and Aldrete recovery scores were recorded every 5min. Neurologic assessment was performed when the Aldrete score was 9-10. Results BIS values were higher, the total coumption of isoflurane were lower, times to fit spontaneous breathing, eye opening, extubation and Aldrete score of 9-10 and adequate neurologic assessment were shorter in the BIS group. Conclusion Titration of isoflurane using BIS monitoring in microscopic traphenoid surgery for pituitary adenoma reduced the isoflurane coumption and shortened the recovery times from general anesthesia an