临床评估五种膜式氧合器在不同温度下的跨膜压差.doc

临床评估五种膜式氧合器在不同温度下的跨膜压差 目录 TOC \o 1-9 \h \z \u 目录 1 正文 1 文1：临床评估五种膜式氧合器在不同温度下的跨膜压差 1 1 资料和方法 3 2 结 果 4 3 讨 论 4 文2：腹腔镜胃癌根治术的临床评估 6 1 资料与方法 6 2 结果 7 3 讨论 7 参考文摘引言： 8 原创性声明（模板） 9 文章致谢（模板） 10 正文 临床评估五种膜式氧合器在不同温度下的跨膜压差 文1：临床评估五种膜式氧合器在不同温度下的跨膜压差 Abstract: OBJECTIVE To evaluate five type commercial available oxygenato of the tra-membrane pressure drop (TMPD) during normothermic and hypothermic cardiopulmonary bypass (CPB). METHODS Forty patients scheduled for cardiac surgery participated this study and were divided into five groups (n=8,in per-group) according to type of oxygenato used during CPB: group J (Joatra Quardox), group A (Affinity NT), group P (Polystan Safe Maxi), group T (Terumo Capiox SX) and group C (COBE APEX-TM). Paramete were collected during CPB including mean arterial pressure, pump flow, temperature, hematocrit and TMPD at pre- and post-oxygenator during normothermic(T1), hypothermic,28 ℃ (T2) and after rewarming (T3). RESULTS There was no significant difference among five groups in pre-operative clinical paramete (P). TMPDs of group J were the lowest in different time-points, followed by the other group were group A group P group T group C. TMPD of group J and A compared to the other three groups were lower (P) respectively and J was significant lower than group A at T2 (P). Except TMPDs of group P were significantly lower than group C (P) at T1, there were no statistical significance (P ) in various time-points. Although TMPDs in group A, P and T during T2 were higher than T1 and T3, but there were no statistical significance (P) in various The TMPD of HFMOs in group J and A produced significantly lower and during normothermic and hypothermic CPB, thus blood trauma with these two HFMOs during CPB may be significantly lower compared to the other three. Key words： Membrane oxygenato; Pressure drop;Cardiopulmonary bypass; Hyperthermia 随着生物医学工程技术的进步，中空纤维膜式氧合器(hollow-fiber membrane oxygenato,HFMO)的走血方式从纤维内走血变为纤维外走血，