TED英文演说-阻止下一次大流行的病毒检测网络中英文演讲稿.docx

第 第 PAGE 1 页 A virus detection network to stop the next pandemic 00:10 [In January 2020, Christian Happi and Pardis Sabeti presented an Audacious idea] 00:16 [Sentinel: An early warning system to detect and track the next pandemic] 00:22 [Heres how it would work ...] 00:25 Christian Happi: Sentinel is a proactive early warning system to preempt pandemics. It is built on three major pillars. 00:35 Pardis Sabeti: The first pillar is Detect. Christian and I have been studying infectious diseases together around the world for two decades. We have been using genome sequencing. Reading out the complete genetic information of a microbe, it allows us to identify viruses, even those weve never seen before, track them as they spread and watch for new mutations. And now with the powerful gene-editing technology CRISPR, we can use this genetic information to rapidly design exquisitely sensitive diagnostic tests for any microbe. 01:06 CH: One of these tools is called SHERLOCK. It can be used to test known viruses on simple paper strips. It is very inexpensive, and frontline health workers can use SHERLOCK to detect the most common or the most threatening viruses within an hour. 01:25 PS: The other tool is CARMEN. It requires a lab, but it can test for hundreds of viruses simultaneously. So hospital lab staff can test patient samples for a broad range of viruses within a day. 01:37 Our second pillar is Connect. Connect everyone and share this information across the public health community. In most outbreaks, hospital staff share case information through paper, Excel -- if at all. This makes tracking an outbreak through space and time and coordinating a response extremely difficult. So were developing a cloud-based system and mobile applications that connect community health workers, clinicians, public health teams -- everyone -- and allows them to upload data, perform analysis, share insights and coordinate a response and action plan in real time. 02:14 CH: Our third