Adiponectin-Receptor-Agonists-Modulators-生命科学试剂-MedChemExpress.pdf

Adiponectin Receptor AdipoRs Adiponectin is a protein which in humans is encoded by the ADIPOQ gene. It is involved in regulating glucose levels as well as fatty acid breakdown. The hormone plays a role in the suppression of the metabolic derangements that may result intype 2 diabetes, obesity, atherosclerosis, non-alcoholic fatty liver disease and an independent risk factor for metabolic syndrome. Adiponectin binds to a number of receptors. Two receptors have been identified with homology to G protein-coupled receptors, and one receptor similar to the cadherin family: adiponectin receptor 1 and adiponectin receptor 2. www.MedChemE 1 Adiponectin Receptor Agonists AdipoRon AdipoRon hydrochloride Cat. No.: HY-15848 Cat. No.: HY-110164 AdipoRon is an orally active adiponectin receptor AdipoRon hydrochloride is an orally active and (AdipoR) agonist, binding to AdipoR1 and AdipoR2 specific AdipoR agonist, binding to AdipoR1 and with K s of 1.8 and 3.1 μM, respectively. AdipoR2, with K s of 1.8 and 3.1 μM, d d respectively. Purity: 99.87% Purity: 98% Clinical Data: No Development Reported