PDGFR-Inhibitors-Modulators-生命科学试剂-MedChemExpress.pdf

PDGFR Platelet-derived growth factor receptor PDGFR (Platelet-derived growth factor receptors) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family. PDGF subunits -A and -B are important factors regulating cell proliferation, cellular differentiation, cell growth, development and many diseases including cancer. There are two forms of the PDGFR: PDGFR alpha and PDGFR beta. www.MedChemE 1 PDGFR Inhibitors (Z)-Orantinib 10Z-Hymenialdisine ((Z)-SU6668; (Z)-TSU-68) Cat. No.: HY-10517A ((Z)-Hymenialdisine; Hymenialdisine) Cat. No.: HY-N6794 (Z)-Orantinib ((Z)-SU6668) is a potent, selective, 10Z-Hymenialdisine ((Z)-Hymenialdisine) is a orally active and ATP competitive inhibitor of natural bioactive pyrrole alkaloid. Flk1/KDR, PDGFRβ, and FGFR1, with IC50s of 2.1, 10Z-Hymenialdisine is a pan kinase inhibitor, and 0.008, and 1.2 µM, respectively. (Z)-Orantinib is has anticancer activities. a potent antiangiogenic and antitumor agent that induces regression of established tumors. Purity: 99.02% Purity: 98% Clinical Data: No Development Reported Clinical Data: No Development Reported Size: 10 mM × 1 mL, 10 mg, 50 mg, 100 mg Size: 1 mg, 5 mg