Lipopolysaccharide-LPS-DataSheet-生命科学试剂-MedChemExpress.pdf

Hotline: 400-820-3792 Inhibitors • Agonists • Screening Libraries www.MedChemE Lipopolysaccharide Cat. No.: HY-D1056 Synonyms: LPS 作⽤靶点: Others 作⽤通路: Others 储存⽅式: Please store the product under the recommended conditions in the COA. BIOLOGICAL ACTIVITY ⽣物活性 Lipopolysaccharide (LPS) 是从⾰兰⽒阴性菌外膜的⼩叶中提取的内毒素 [1] [2] [3]。Lipopolysaccharide 由⼀ 个抗原 O- 特异性链、⼀个核⼼寡糖和脂质 A 构成。Lipopolysaccharide 是⼀种⾼度免疫原性抗原，可增强免 疫反应 [4] [5]。 REFERENCES [1]. Rietschel ET, et al. Bacterial endotoxin: molecular relationships of structure to activity and function. FASEB J. 1994 Feb;8(2):217-25. [2]. Kabanov DS, et al. Structural analysis of lipopolysaccharides from Gram-negative bacteria. Biochemistry (Mosc). 2010 Apr;75(4):383- 404. [3]. Heinrichs DE, et al. Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica. Mol Microbiol. 1998 Oct;30(2):221-32. [4]. Kajiwara Y, et al. A critical role for human caspase-4 in endotoxin sensitivity. J Immunol. 2014 Jul 1;193(1):335-43. [5]. Lai HT, et al. Effects of repeated intratracheally administered lipopolysaccharide on primary and secondary specific antibody responses and on body weight ga