AZD5904-DataSheet-生命科学试剂-MedChemExpress.pdf

Hotline: 400-820-3792 Inhibitors • Agonists • Screening Libraries www.MedChemE AZD5904 Cat. No.: HY-111341 CAS No.: 618913-30-7 分⼦式: C₁₀H₁₂N₄O₂S 分⼦量: 252.29 作⽤靶点: Glutathione Peroxidase 作⽤通路: Metabolic Enzyme/Protease 储存⽅式: Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month 溶解性数据 体外实验 DMSO : 125 mg/mL (495.46 mM; Need ultrasonic and warming) Mass Solvent 1 mg 5 mg 10 mg Concentration 制备储备液 1 mM 3.9637 mL 19.8185 mL 39.6369 mL 5 mM 0.7927 mL 3.9637 mL 7.9274 mL 10 mM 0.3964 mL 1.9818 mL 3.9637 mL 请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存⽅式和期限。 BIOLOGICAL ACTIVITY ⽣物活性 AZD5904 是⼀种有效且不可逆的⼈髓过氧化物酶 (MPO) 抑制剂，其 IC50 值为 140 nM，在⼩⿏和⼤⿏中也具 有相似的效⼒。 IC50 Target IC50: 140 nM (human MPO) [1] 体外研究 AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO) with an IC50 of 140 nM and has simila