（修改稿20230904）头部伽玛刀治疗肺腺癌脑转移瘤的专家共识.docx

头部伽玛刀治疗肺腺癌脑转移瘤的专家共识 脑转移瘤是一种恶性肿瘤，是原发肿瘤的癌细胞通过血管或淋巴系统转移到脑部，形成的肿瘤。由于肺腺癌脑转移瘤具有中等程度的放射敏感性，加上患者的病程和对系统治疗的反应具有自身特征，因此如何规范地采取头部伽玛刀治疗肺腺癌脑转移瘤，进而获得最优的肿瘤控制效果和最大程度的神经功能保护，仍有一系列问题需要明确。基于这个原因，世界华人神经外科协会放射外科专业委员会牵头，联合头部伽玛刀和相关学科的专家共同讨论，形成这一共识，为国内伽玛刀治疗中心规范治疗肺腺癌脑转移瘤提供参考。 肺腺癌脑转移的流行病学 脑转移瘤是成人颅内最常见的肿瘤之一 ADDIN EN.CITE ADDIN EN.CITE.DATA [1]。对原发肿瘤的有效控制使生存时间延长，同时，影像检查的进步使肺癌脑转移瘤的检出率增高，这些原因成为肺癌脑转移瘤发病率日益增长的因素 ADDIN EN.CITE EndNoteCiteAuthorRiessk/AuthorYear2013/YearRecNum219/RecNumDisplayTextstyle face=superscript[2]/style/DisplayTextrecordrec-number219/rec-numberforeign-keyskey app=EN db-id=2af0zw9tnas2pgevz0150dzsxwr52xrxtv0a timestamp=1691271664219/key/foreign-keysref-type name=Journal Article17/ref-typecontributorsauthorsauthorRiessk, J./author/authors/contributorsauth-address4501 X St, Ste 3016, Sacramento, CA 95817. E-mail: Jonathan.Riess@./auth-addresstitlestitleShifting paradigms in non-small cell lung cancer: an evolving therapeutic landscape/titlesecondary-titleAm J Manag Care/secondary-title/titlesperiodicalfull-titleAm J Manag Care/full-title/periodicalpagess390-7/pagesvolume19/volumenumber19 Suppl/numberedition2014/02/06/editionkeywordskeywordCarcinoma, Non-Small-Cell Lung/epidemiology/*secondary/*therapy/keywordkeywordChemotherapy, Adjuvant/keywordkeywordCombined Modality Therapy/keywordkeywordDisease-Free Survival/keywordkeywordFemale/keywordkeywordGenes, erbB-1/*drug effects/keywordkeywordHumans/keywordkeywordLung Neoplasms/epidemiology/*pathology/*therapy/keywordkeywordMale/keywordkeywordMolecular Targeted Therapy/keywordkeywordNeoplasm Invasiveness/pathology/keywordkeywordNeoplasm Metastasis/keywordkeywordNeoplasm Staging/keywordkeywordPneumonectomy/methods/keywordkeywordPrognosis/keywordkeywordRadiotherapy, Adjuvant/keywordkeywordSurvival Analysis/keyword/keywordsdatesyear2013/yearpub-datesdateDec/date/pub-dates/datesisbn1936-2692 (Electronic)#xD;1088-0224 (Linking)/isbnaccession-nuaccession-numurlsrelated-urlsurl/pubmedurl/related-urls/urls/record/Cite/E