皮肤性病学课件：接触性皮炎（英文版）.pptVIP

Contact Dermatitis Clinical manifestationDiagnosisTherapy Definition Contact dermatitis indicates that people get in touch with some substances leads to acute or chronic inflammation on the skin or/and mucosa. Contact dermatitis represents a spectrum of inflammatory skin reactions induced by exposure to external substances. Etiologyallergiesirritants animal allergiesplant allergieschemical allergies PathogenisisIrritant contact dermatitis Substances themselves are irritant or toxic;the eruptions can occur on everybody who gets in touch with them.Allergic contact dermatitis It shows typical allergic reaction type IV. Substances are allergen,only a few people will be attacked who contact them. primary irritant irritant or toxic occur on everybody allergic reaction type IV delayed-type hypersensitivity reaction allergen only a few people clinical manifestation Acute contact dermatitis It always occurs quickly, erythema, papule ,papulovesicle can be seen on contact place , boundary of the lesion is very clear. Subacute and chronic contact dermatitis Because the concentrations or thrill of contactile substances are low ,so lesions can show subacute characters, like erythema ,papule ; another reason is that contact time is long ,then lesion become chronic eczamatoid styles; like mild proliferation and lichenification. chronic phase ichenification Diagnosis History feature of lesions patch test Treatment The criteria therapy is try to find causes, manage to eliminate contact of the skin with stimulator and sensitive substances,antihistamine drugs are necessary for general use. avoidance topical antipruritics. topical corticosteroids.oral antihistaminessystemic corticosteroids systemic treatment antihistamine drugs antipruritics. systemic corticosteroids topical treatmentErythema------calamine lotion Exude --------3%boric