医学英语医英immunesystemppt课件.pptxVIP

Gang XIN Department of Microbiology and Immunology gxin@Lymphatic/Immune system deaths of an estimated 300 to 500 million people Smallpox Edward Jenner Father of Immunology 1749- 1823 1802 caricature of Jenner vaccinating patients who feared it would make them sprout cowlike appendages. L. vaccinus, relating to a cow, vacca /wiki/Edward_Jenner In 1796 The announcement by the WHO that smallpox was the first disease that had been eradicated worldwide by a program of vaccination 1979.10.26 Louis Pasteur The “Father” of the Modern Microbiology 1822- 1895 Vaccines: 1880, chicken cholera 1881, anthrax 1885, rabies consciously immune system What is it? Where is it? How does it work? What is immunity? n IMMUNITY ←← IMMUNIS (EXEMPT) üLatin: Protection from legal prosecution üNow, in medical terms: free of disease. n Immune system n Immune response n Immunology n Immunologist n Immunodeficiency n Immunocompromised immunity congenital immunodeficiency present at birth /wgbh/amex/bubble/peopleevents/p_vetter.html severe combined immunodeficiency (SCID) ØInfection ØLymphoma Bubble boy David Vetter(1971~1984) n HIV - human immunodeficiency virus n AIDS - acquired immune deficiency syndrome ARC is A prodromal phase of effects phase of infection with HIV. Symptoms can include recurring fever, unexplained weight loss, swollen lymph glands, diarrhea, or fungal infection of the mouth. ARC: AIDS-related complex Candida infections n Fungal, bacterial, viral and protozoal infection n The most frequent opportunistic tumour, Kaposis sarcoma, is observed in 20% of patients with AIDS. n Malignant lymphomas are also frequently seen in AIDS patients. Opportunity Infection and Cancer Kaposi’s sarcoma Kaposi’s sarcoma Kaposis sarcoma on the skin of an AIDS patient. lymphoma n immune defence üdefense agaist infectious diseases n immune surveillance ükill cancer cells n immun