2023 SABCS 乳腺癌必威体育精装版进展_1.pdf

SANANTONIOBREASTCANCERSYMPOSIUM

2023

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HRMA-202312009

•GS01-01ERHER2±CheckMate7FL

•GS01-02ER+/HER2-IIIKEYNOTE-

756

•GS01-03-

•GS03-03+NSAIHR+/HER2-NATALEEiDFS

•GS03-12T-DM1HER2non-pCRHER2III:KATHERINEIDFSOS

•LBO1-01IIIKEYNOTE-522EFS

•LBO1-02HER2(pCR)APTneoMichelangelo

•LBO1-03(N)2+CbP12vs+CbP(TNBC)II:

(BCT1902/IBCSG61-20Neo-N)

•PO1-01-09avelumabII/IIIImmunoADAPT

•PO1-03-11++

•PO1-28-04PILHLE-001HRHER2IHC2+/FISHII

•PO2-01-05HER2

•PO2-02-05CDK4/6II-IIIHR+/HER2-

•PO3-02-12HRHER2

•PO3-18-03/:

•PO5-01-04HER2/HER2HER2

HRMA-202312009

SANANTONIOBREASTCANCERSYMPOSIUM

•GS01-05TNBC

KEYLYNK-009

•GS01-10HER2CLIMB-02:T-DM1HER23

•GS01-12MONARCH3:HR+HER2-

•RF01-03PARSIFAL-LONGPARSIFAL+vs+HR/HER2

•RF01-06PD-1?

•RF02-01(HR)HER2(ASPIRE)I/Il

•LBO1-04Zanidatamab+HR+mBC

•PS12-08MORPHEUS±Ib/II

•PS15-03Vepdegestrant(ER)(PROTAC)ER/2(HER2)1b

•PS17-03CapivasertibHR/HER23CAPItellO-291PlK3CA/AKT1/PTEN

PFS

•PO1-04-04HER2II

•PO1-04-05++HER2

•PO1-19-04CDK4/6HR+/HER2-Ib

•PO2-05-01HR+/HER2-

•PO4-04-04her2

•PO4-04-07HER2

HRMA-202312009

SANANTONIOBREASTCANCERSYMPOSIUM

ADC

•GS02-01DatopotamabderuxtecanDato-DXdHER2-HR+/HER2-

BC3TROPION-Breast01

•RF02-03(T-DXd)HER2HR+/:1b(DESTINY-

Breast08)

•PS08-01-(ADCs):

•PS08-04HER2(MBC)(ADCs)(T-DXd)(SG)

HRMA-202312009