孕早期空腹血糖值对妊娠期糖尿病的预测价值 .pdf

孕早期空腹血糖值对妊娠期糖尿病的预测价值

喻茜;牛晓虎;冯佩;许锬

【摘要】AbstractObjectiveTothepredictivevalueoffastingblood

glucoseinfirsttrimesterforgestationaldiabetesmellitus(GDM).Methods

975pregnantwomenwhotookthefirsttrimesterexaminationwithin13

weeksinkunshancommunityhealthservicecentrefromOctober7,2014to

April30,2015werestudiedbyclustersampling.Maternal

age,height,weight,systolicbloodpressure,diastolicbloodpressure,fasting

plasmaglucoseatthefirsttrimesterexaminationandOGTTdatawere

collected.Thecorrelationbetweenfirsttrimesterfastingplasmaglucose

andgesta-tionaldiabetesmellituswereanalyzedbyusingunivariateand

multivariateanalysis.Thefirsttrimesterfastingplasmaglucosepredictiveof

gestationaldiabetesmellituswasanalyzedbyreceiveroperating

characteristiccurve(ROC).Re-sultsTheaveragematernalage,BMI,systolic

bloodpressure,diastolicbloodpressure,hemoglobin,fastingplasma

glucose(FPG)atthefirsttrimesterexaminationinGDMgroupwerehigher

thanthatofthecontrolgroup(P0.05).Therewerenosignificance

differenceingestationalage,gestationweightgain,theHba1catthefirst

trimes-terexamination,theculturelevelandtheoccupationbetweenthe

twogroups(P0.05).TheFPG,theplasmaglucoseof1hourlater,the

plasmaglucoseof2hourlaterin24~28weekswereincreasedalongwith

theincreasingfastingplasmaglucoseatthefirsttrimester

examination.ROCcurveanalysisshowedthattheareaofundertheROC

curvewas0.666(95%CI:0.636~0.696,P0.001),and4.74mmol/Listhe

mostappropriatecut-offpointtopredicttheincidenceofGDM.Conclusion

Theplasmaglucoseatthefirsttrimesterexaminationwaspositivelycorre-

latedwiththeplasmaglucosein24~28weeks.Thefirsttrimesterfasting

glucoselevelmayhelpidentifyGDMinlaterpregnancy.%目的：探究孕早期

空腹血糖值对妊娠期糖尿病的预测价值。方法采取整群随机抽样的方法，抽取

2014年10月7日－2015年4月30日在昆山市玉山镇社区卫生服务中心、张浦

社区卫生服务中心进行首次产检（