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5382023505 Cancer Res Prev Treat,2023,Vol.50,No.5
··肿瘤防治研究年第卷第期
doi:10.3971/j.issn.1000-8578.2023.22.1152·综 述·
醋酸阿比特龙与多西他赛治疗转移性激素
敏感性前列腺癌患者的真实世界研究进展
11,21,2
马东升，安恒庆，王玉杰
ProgressinAReal-worldStudyofAbirateroneAcetateVersusDocetaxelinPatientswith
MetastaticHormone-sensitiveProstateCancer
MA Dongsheng11,21,2
, AN Hengqing, WANG Yujie
1.DepartmentofUrology,TheFirstAffiliatedHospitalofXinjiangMedicalUniversity,
Urumqi830054,China;2.XinjiangClinicalMedicalResearchCenterforMaleGermline
Diseases,Urumqi830054,China
CorrespondingAuthor:WANGYujie,E-mail:******************.com
Abstract:The safety and survival benefits of abiraterone acetate and docetaxel in the treatment of patients
with metastatic hormone-sensitive prostate cancer have been confirmed by randomized controlled trials and
clinical studies abroad. However, real-world studies remain lacking. In this article, we review the progress of
real-world studies of abiraterone acetate and docetaxel in the treatment of patients with metastatic hormone-
sensitive prostate cancer and the problems faced in clinical practice against the background of differentiated
real-world studies. Further research is needed to address clinically important issues, such as individualized
dosing, combination dosing, and monitoring of adverse effects.
Keywords: Prostate cancer; Abiraterone acetate; Docetaxel; Real-world study; Drug evaluation
Funding: Natural Science Foundation of Xinjiang Uygur Autonomous Region (No. 2020D01C158); Key Project
of the Natural Science Foundation of Xinjiang Uygur Autonomous Region (No. 2022D01D39); Construction
Project of Xinjiang Clinical Medical Research Centre for Urogenital Diseases in Male Genital System
Competinginterests: The au
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