Tolfenamic-Acid-Standard-GEA-6414-Standard-DataSheet-生命科学试剂-MCE.pdf

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TolfenamicAcid(Standard)

Cat.No.:HY-B0335R

CASNo.:13710-19-5

Synonyms:GEA6414(Standard)

分⼦式:C₁₄H₁₂ClNO₂

分⼦量:261.7

作⽤靶点:COX

作⽤通路:Immunology/Inflammation

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

溶解性数据

体外实验DMSO:≥100mg/mL(382.12mM)

H2O:0.1mg/mL(insoluble)

*≥meanssoluble,butsaturationunknown.

Mass

Solvent

1mg5mg10mg

Concentration

制备储备液1mM3.8212mL19.1058mL38.2117mL

5mM0.7642mL3.8212mL7.6423mL

10mM0.3821mL1.9106mL3.8212mL

BIOLOGICALACTIVITY

⽣物活性TolfenamicAcid(Standard)是TolfenamicAcid的分析标准品。本产品⽤于研究及分析应⽤。Tolfenamic

Acid(GEA6414)是⼀种⾮甾体抗炎剂和抗癌剂，能够选择性地抑制COX-2的活性，在LPS诱导的⽝DH82单

核细胞/巨噬细胞中，对COX-2的IC50值为13.49μM(3.53μg/mL)，对COX-1⽆作⽤。